[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Chio et al., 2017 - Google Patents

Mechanisms of tail-anchored membrane protein targeting and insertion

Chio et al., 2017

View PDF
Document ID
5368418156808914131
Author
Chio U
Cho H
Shan S
Publication year
Publication venue
Annual review of cell and developmental biology

External Links

Snippet

Proper localization of membrane proteins is essential for the function of biological membranes and for the establishment of organelle identity within a cell. Molecular machineries that mediate membrane protein biogenesis need to not only achieve a high …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Similar Documents

Publication Publication Date Title
Chio et al. Mechanisms of tail-anchored membrane protein targeting and insertion
Beaulieu et al. Structural and biophysical insights into the function of the intrinsically disordered Myc oncoprotein
Fernández-Fernández et al. Hsp70 chaperone: a master player in protein homeostasis
Brunger et al. Molecular mechanisms of fast neurotransmitter release
Kuhn et al. Targeting and insertion of membrane proteins
Klammt et al. High level cell‐free expression and specific labeling of integral membrane proteins
Stevers et al. Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR
Xu et al. The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling
Dawidowski et al. Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites
Hegde The function, structure, and origins of the ER membrane protein complex
Schönichen et al. Considering protonation as a posttranslational modification regulating protein structure and function
Uversky et al. Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling
Shen et al. Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response
Ganji et al. The VCP-UBXN1 complex mediates triage of ubiquitylated cytosolic proteins bound to the BAG6 complex
Luna et al. The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes
Opoku-Nsiah et al. The YΦ motif defines the structure-activity relationships of human 20S proteasome activators
Shirnekhi et al. The role of phase-separated condensates in fusion oncoprotein–driven cancers
Wei et al. Avoiding drug resistance through extended drug target interfaces: a case for stapled peptides
Knorr et al. The dynamic architecture of Map1-and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains
Khodjoyan et al. Investigation of the fuzzy complex between rsv nucleoprotein and phosphoprotein to optimize an inhibition assay by fluorescence polarization
Nyarko Differential binding affinities and allosteric conformational changes underlie interactions of Yorkie and a multivalent PPxY partner
Seal et al. A staphylococcal cyclophilin carries a single domain and unfolds via the formation of an intermediate that preserves cyclosporin A binding activity
Bai et al. Structural insights into the membrane chaperones for multi-pass membrane protein biogenesis
CA3060372C (en) Improved methods for generating small molecule degraders and dimerizers
Brugger et al. Structure of phosphorylated-like RssB, the adaptor delivering σs to the ClpXP proteolytic machinery, reveals an interface switch for activation