Behara et al., 2011 - Google Patents
An approach to characterising the cohesive behaviour of powders using a flow titration aerosolisation based methodologyBehara et al., 2011
- Document ID
- 5243540811614150108
- Author
- Behara S
- Larson I
- Kippax P
- Morton D
- Stewart P
- Publication year
- Publication venue
- Chemical Engineering Science
External Links
Snippet
The purpose of this study was to characterise the cohesive behaviour of powders by measuring aerosolisation at a sequence of different flow rates, ie flow titration. Salbutamol sulphate and Lactohale 300 were model cohesive materials. Laser diffraction particle sizing …
- 239000000843 powder 0 title abstract description 110
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Behara et al. | An approach to characterising the cohesive behaviour of powders using a flow titration aerosolisation based methodology | |
| Zhou et al. | Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach | |
| Karner et al. | The impact of electrostatic charge in pharmaceutical powders with specific focus on inhalation-powders | |
| Shah et al. | Influence of particle properties on powder bulk behaviour and processability | |
| Wong et al. | Electrostatics in pharmaceutical solids | |
| Wong et al. | Electrostatics in pharmaceutical aerosols for inhalation | |
| Sheth et al. | Factors influencing aerodynamic particle size distribution of suspension pressurized metered dose inhalers | |
| Sarkar et al. | On the role of forces governing particulate interactions in pharmaceutical systems: A review | |
| Stein et al. | A model for predicting size distributions delivered from pMDIs with suspended drug | |
| Stegemann et al. | Focusing on powder processing in dry powder inhalation product development, manufacturing and performance | |
| Kwek et al. | High speed imaging with electrostatic charge monitoring to track powder deagglomeration upon impact | |
| Tong et al. | CFD-DEM study of the aerosolisation mechanism of carrier-based formulations with high drug loadings | |
| Behara et al. | Insight into pressure drop dependent efficiencies of dry powder inhalers | |
| Suwandecha et al. | Effect of turbulent kinetic energy on dry powder inhaler performance | |
| Hickey et al. | A guide to pharmaceutical particulate science | |
| Ung et al. | Design of spray dried insulin microparticles to bypass deposition in the extrathoracic region and maximize total lung dose | |
| Wong et al. | Measuring bipolar charge and mass distributions of powder aerosols by a novel tool (BOLAR) | |
| Chow et al. | In vitro-in vivo correlation of cascade impactor data for orally inhaled pharmaceutical aerosols | |
| Leung et al. | Understanding the different effects of inhaler design on the aerosol performance of drug-only and carrier-based DPI formulations. Part 1: grid structure | |
| Fromen et al. | Synthesis and characterization of monodisperse uniformly shaped respirable aerosols | |
| Lowe et al. | Fragmentation dynamics of single agglomerate-to-wall impaction | |
| Chow et al. | Investigation of electrostatic behavior of a lactose carrier for dry powder inhalers | |
| Chen et al. | Investigation of dry powder aerosolization mechanisms in different channel designs | |
| Zhu et al. | Numerical investigation of powder dispersion mechanisms in Turbuhaler and the contact electrification effect | |
| Behara et al. | The kinetics of cohesive powder de-agglomeration from three inhaler devices |