Khmaladze et al., 2014 - Google Patents
Hyperspectral imaging and characterization of live cells by broadband coherent anti-Stokes Raman scattering (CARS) microscopy with singular value decomposition …Khmaladze et al., 2014
View PDF- Document ID
- 5155079120278706537
- Author
- Khmaladze A
- Jasensky J
- Price E
- Zhang C
- Boughton A
- Han X
- Seeley E
- Liu X
- Holl M
- Chen Z
- Publication year
- Publication venue
- Applied spectroscopy
External Links
Snippet
Coherent anti-Stokes Raman scattering (CARS) microscopy can be used as a powerful imaging technique to identify chemical compositions of complex samples in biology, biophysics, medicine, and materials science. In this work we developed a CARS …
- 238000001069 Raman spectroscopy 0 title abstract description 26
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N2021/653—Coherent methods [CARS]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colour
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry; Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Khmaladze et al. | Hyperspectral imaging and characterization of live cells by broadband coherent anti-Stokes Raman scattering (CARS) microscopy with singular value decomposition (SVD) analysis | |
| Borile et al. | Label-free multiphoton microscopy: much more than fancy images | |
| Schie et al. | Methods and applications of Raman microspectroscopy to single-cell analysis | |
| Shipp et al. | Raman spectroscopy: techniques and applications in the life sciences | |
| Matousek et al. | Noninvasive Raman spectroscopy of human tissue in vivo | |
| Downes et al. | Raman spectroscopy and related techniques in biomedicine | |
| Diem et al. | Infrared spectroscopy of cells and tissues: shining light onto a novel subject | |
| Bocklitz et al. | Raman based molecular imaging and analytics: a magic bullet for biomedical applications!? | |
| Camp Jr et al. | High-speed coherent Raman fingerprint imaging of biological tissues | |
| Hirschfeld et al. | FT-Raman spectroscopy: development and justification | |
| Meyer et al. | Nonlinear microscopy, infrared, and Raman microspectroscopy for brain tumor analysis | |
| Pohling et al. | Chemoselective imaging of mouse brain tissue via multiplex CARS microscopy | |
| Keller et al. | Spatially offset Raman spectroscopy of layered soft tissues | |
| Elumalai et al. | Raman microscopy: progress in research on cancer cell sensing | |
| Pascut et al. | Toward label-free Raman-activated cell sorting of cardiomyocytes derived from human embryonic stem cells | |
| Gala de Pablo et al. | Biochemical fingerprint of colorectal cancer cell lines using label‐free live single‐cell Raman spectroscopy | |
| Rusciano et al. | Raman tweezers as a diagnostic tool of hemoglobin-related blood disorders | |
| Marcott et al. | Localization of human hair structural lipids using nanoscale infrared spectroscopy and imaging | |
| Kuzmin et al. | Ramanomics: new omics disciplines using micro Raman spectrometry with biomolecular component analysis for molecular profiling of biological structures | |
| Pavillon et al. | Maximizing throughput in label-free microspectroscopy with hybrid Raman imaging | |
| Pence et al. | Multi-window sparse spectral sampling stimulated Raman scattering microscopy | |
| O’Dwyer et al. | Automated raman micro-spectroscopy of epithelial cell nuclei for high-throughput classification | |
| Miyazaki et al. | Photothermal microscopy for high sensitivity and high resolution absorption contrast imaging of biological tissues | |
| Kang et al. | Investigating effects of proteasome inhibitor on multiple myeloma cells using confocal Raman microscopy | |
| Sowoidnich et al. | Shifted excitation raman difference spectroscopy with charge-shifting charge-coupled device (CCD) lock-in detection |