[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Malik et al., 2011 - Google Patents

Design and synthesis of a near-infrared fluorescent nanofiber precursor for detecting cell-secreted urokinase activity

Malik et al., 2011

View PDF
Document ID
4957671055247338974
Author
Malik R
Qian S
Law B
Publication year
Publication venue
Analytical biochemistry

External Links

Snippet

Abnormal proteolysis is often observed during disease progression. Up-regulation of certain tumor-associated proteases such as urokinase plasminogen activator (uPA) can be a hallmark of malignant transformation. Here we report the design and synthesis of a near …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/574—Immunoassay; Biospecific binding assay for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/30—Macromolecular compounds
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin, zein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue

Similar Documents

Publication Publication Date Title
Li et al. Potent retro-inverso D-peptide for simultaneous targeting of angiogenic blood vasculature and tumor cells
Sugahara et al. Tissue-penetrating delivery of compounds and nanoparticles into tumors
Yao et al. Building stable MMP2-responsive multifunctional polymeric micelles by an all-in-one polymer–lipid conjugate for tumor-targeted intracellular drug delivery
Law et al. Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter
Wang et al. A prodrug-type, MMP-2-targeting nanoprobe for tumor detection and imaging
AU2018248327B2 (en) Methods to spatially profile protease activity in tissue and sections
Zhang et al. Enhanced cellular entry and efficacy of tat conjugates by rational design of the auxiliary segment
Zhang et al. Identification of a bladder cancer-specific ligand using a combinatorial chemistry approach
Malik et al. Design and synthesis of a near-infrared fluorescent nanofiber precursor for detecting cell-secreted urokinase activity
Thévenin et al. pHLIP-mediated translocation of membrane-impermeable molecules into cells
Cho et al. Activatable iRGD-based peptide monolith: Targeting, internalization, and fluorescence activation for precise tumor imaging
US20160160263A1 (en) Personalized protease assay to measure protease activity in neoplasms
ES2696623T3 (en) Functionalized liposomes useful for the administration of bioactive compounds
Yue et al. Inducible graphene oxide probe for high-specific tumor diagnosis
Cao et al. Enzyme-induced morphological transformation of self-assembled peptide nanovehicles potentiates intratumoral aggregation and inhibits tumour immunosuppression
Bratovš et al. Stefin A-functionalized liposomes as a system for cathepsins S and L-targeted drug delivery
Falciani et al. Nanoparticles exposing neurotensin tumor‐specific drivers
Guo et al. Bradykinin-Potentiating Peptide-Paclitaxel Conjugate Directed at Ectopically Expressed Angiotensin-Converting Enzyme in Triple-Negative Breast Cancer
CN110227162A (en) Target excretion body and preparation method, application, drug delivery system and drug
Tian et al. An intracellularly activatable, fluorogenic probe for cancer imaging
He et al. Enhanced Tumor Targeting and Penetration of Proteolysis-Targeting Chimeras through iRGD Peptide Conjugation: A Strategy for Precise Protein Degradation in Breast Cancer
Feng et al. Ultrasound Molecular Imaging of Bladder Cancer via Extradomain B Fibronectin-Targeted Biosynthetic GVs
Soendergaard et al. In vitro high throughput phage display selection of ovarian cancer avid phage clones for near-infrared optical imaging
Ortner et al. VPAC receptor mediated tumor cell targeting by protamine based nanoparticles
Zhao et al. A novel strategy to tag matrix metalloproteinases-positive cells for in vivo imaging of invasive and metastatic activity of tumor cells