Velanac et al., 2012 - Google Patents
Bace1 processing of NRG1 type III produces a myelin‐inducing signal but is not essential for the stimulation of myelinationVelanac et al., 2012
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- 4905641538551609287
- Author
- Velanac V
- Unterbarnscheidt T
- Hinrichs W
- Gummert M
- Fischer T
- Rossner M
- Trimarco A
- Brivio V
- Taveggia C
- Willem M
- Haass C
- Möbius W
- Nave K
- Schwab M
- Publication year
- Publication venue
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Myelin sheath thickness is precisely adjusted to axon caliber, and in the peripheral nervous system, neuregulin 1 (NRG1) type III is a key regulator of this process. It has been proposed that the protease BACE1 activates NRG1 dependent myelination. Here, we characterize the …
- 102400000058 Neuregulin-1 0 title abstract description 180
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- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
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- C12N5/0619—Neurons
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- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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