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Morgan et al., 2017 - Google Patents

mRNA 3′ uridylation and poly (A) tail length sculpt the mammalian maternal transcriptome

Morgan et al., 2017

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Document ID
4802827712513309593
Author
Morgan M
Much C
DiGiacomo M
Azzi C
Ivanova I
Vitsios D
Pistolic J
Collier P
Moreira P
Benes V
Enright A
O’Carroll D
Publication year
Publication venue
Nature

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Snippet

A fundamental principle in biology is that the program for early development is established during oogenesis in the form of the maternal transcriptome,. How the maternal transcriptome acquires the appropriate content and dosage of transcripts is not fully understood. Here we …
Continue reading at www.ncbi.nlm.nih.gov (HTML) (other versions)

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
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