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Etrych et al., 2007 - Google Patents

Star-shaped immunoglobulin-containing HPMA-based conjugates with doxorubicin for cancer therapy

Etrych et al., 2007

Document ID
4682283421771231760
Author
Etrych T
Mrkvan T
Říhová B
Ulbrich K
Publication year
Publication venue
Journal of controlled release

External Links

Snippet

Synthesis and preliminary anticancer activity of new star-shaped immunoglobulin-containing polymer–doxorubicin (DOX) conjugates were investigated. The polymer precursors used for the synthesis of immunoglobulin–polymer–drug conjugates are based on N-(2 …
Continue reading at www.sciencedirect.com (other versions)

Classifications

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    • A61K47/48169—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being an organic macromolecular compound, i.e. an oligomeric, polymeric, dendrimeric molecule
    • A61K47/48192—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being an organic macromolecular compound, i.e. an oligomeric, polymeric, dendrimeric molecule the organic macromolecular compound has been obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas, polyurethanes
    • A61K47/48215—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being an organic macromolecular compound, i.e. an oligomeric, polymeric, dendrimeric molecule the organic macromolecular compound has been obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas, polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer, dendrimer, e.g. PEG, PPG, PEO, polyglycerol
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