Ventura et al., 2006 - Google Patents
Long-lived C. elegans mitochondrial mutants as a model for human mitochondrial-associated diseasesVentura et al., 2006
View PDF- Document ID
- 4500253734136361131
- Author
- Ventura N
- Rea S
- Testi R
- Publication year
- Publication venue
- Experimental gerontology
External Links
Snippet
Mitochondria play a pivotal role in the life of cells, controlling diverse processes ranging from energy production to the regulation of cell death. In humans, numerous pathological conditions have been linked to mitochondrial dysfunction. Cancer, diabetes, obesity …
- 230000002438 mitochondrial 0 title abstract description 139
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Ventura et al. | Long-lived C. elegans mitochondrial mutants as a model for human mitochondrial-associated diseases | |
Senchuk et al. | Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans | |
Van Raamsdonk et al. | Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans | |
Ventura et al. | p53/CEP‐1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress | |
Martin et al. | Recent advances in the genetics of Parkinson's disease | |
Bratic et al. | Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development | |
Gidalevitz et al. | Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity | |
Vaccaro et al. | TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans | |
Tóth et al. | Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans | |
Zhou et al. | Longevity and stress in Caenorhabditis elegans | |
Vaccaro et al. | Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio | |
Tsang et al. | Mitochondrial respiratory chain deficiency inCaenorhabditis elegans results in developmental arrest and increased life span | |
Lim et al. | Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease | |
Van Raamsdonk et al. | Decreased energy metabolism extends life span in Caenorhabditis elegans without reducing oxidative damage | |
Staab et al. | The conserved SKN-1/Nrf2 stress response pathway regulates synaptic function in Caenorhabditis elegans | |
Tauffenberger et al. | Heritable transmission of stress resistance by high dietary glucose in Caenorhabditis elegans | |
Ventura et al. | Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans | |
Yunger et al. | Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7 | |
Morfini et al. | Polyglutamine expansion diseases: failing to deliver | |
Huang et al. | Mutations in the C. elegans succinate dehydrogenase iron–sulfur subunit promote superoxide generation and premature aging | |
SenGupta et al. | Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology | |
Twumasi‐Boateng et al. | An age‐dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan | |
Kondo et al. | Effect of oxidative stress on translocation of DAF-16 in oxygen-sensitive mutants, mev-1 and gas-1 of Caenorhabditis elegans | |
Ren et al. | Reduction of mitoferrin results in abnormal development and extended lifespan in Caenorhabditis elegans | |
Kim et al. | Transcriptional regulation and life-span modulation of cytosolic aconitase and ferritin genes in C. elegans |