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Edvinsson, 2005 - Google Patents

Clinical data on the CGRP antagonist BIBN4096BS for treatment of migraine attacks

Edvinsson, 2005

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Document ID
4446677891781970835
Author
Edvinsson L
Publication year
Publication venue
CNS drug reviews

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Snippet

Basal studies have shown that calcitonin gene‐related peptide (CGRP) is a major sensory neuronal messenger in the trigeminovascular system, the pathway conveying intracranial pain. In migraine and cluster headache attacks, CGRP is released in parallel with the pain …
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    • A61K31/404—Indoles, e.g. pindolol
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