Pettersson et al., 2009 - Google Patents
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cellsPettersson et al., 2009
View PDF- Document ID
- 4406000612881596421
- Author
- Pettersson H
- Pietras A
- Munksgaard Persson M
- Karlsson J
- Johansson L
- Shoshan M
- Pahlman S
- Publication year
- Publication venue
- Molecular cancer therapeutics
External Links
Snippet
Small cell lung carcinoma (SCLC) is an extremely aggressive form of cancer and current treatment protocols are insufficient. SCLC have neuroendocrine characteristics and show phenotypical similarities to the childhood tumor neuroblastoma. As multidrug-resistant …
- 208000000587 Small Cell Lung Carcinoma 0 title abstract description 117
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/574—Immunoassay; Biospecific binding assay for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Pettersson et al. | Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells | |
Xia et al. | Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation | |
Sadahiro et al. | Activation of the receptor tyrosine kinase AXL regulates the immune microenvironment in glioblastoma | |
Jiang et al. | Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway | |
Taverna et al. | Amphiregulin contained in NSCLC-exosomes induces osteoclast differentiation through the activation of EGFR pathway | |
Santofimia-Castaño et al. | Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis | |
Choi et al. | Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer | |
Jin et al. | The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasis | |
Huang et al. | BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells | |
Mueller et al. | Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer | |
Rajeshkumar et al. | A combination of DR5 agonistic monoclonal antibody with gemcitabine targets pancreatic cancer stem cells and results in long-term disease control in human pancreatic cancer model | |
Tsuboki et al. | Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages | |
Liu et al. | Amlexanox, a selective inhibitor of IKBKE, generates anti-tumoral effects by disrupting the Hippo pathway in human glioblastoma cell lines | |
Deng et al. | N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling | |
Qin et al. | Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway | |
Carter et al. | Synergistic targeting of AML stem/progenitor cells with IAP antagonist birinapant and demethylating agents | |
Friesen et al. | Methadone, commonly used as maintenance medication for outpatient treatment of opioid dependence, kills leukemia cells and overcomes chemoresistance | |
Karpel-Massler et al. | PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma | |
Sato et al. | DPP8 is a novel therapeutic target for multiple myeloma | |
Zhu et al. | Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT | |
Heaney et al. | Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells | |
Chen et al. | Serum deprivation-response protein induces apoptosis in hepatocellular carcinoma through ASK1-JNK/p38 MAPK pathways | |
Stang et al. | Interferon regulatory factor-1-induced apoptosis mediated by a ligand-independent fas-associated death domain pathway in breast cancer cells | |
Xu et al. | Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma | |
Zhu et al. | Inhibition of growth and metastasis of colon cancer by delivering 5-fluorouracil-loaded pluronic P85 copolymer micelles |