Evrard et al., 2018 - Google Patents
Developmental analysis of bone marrow neutrophils reveals populations specialized in expansion, trafficking, and effector functionsEvrard et al., 2018
View HTML- Document ID
- 4360633923510794144
- Author
- Evrard M
- Kwok I
- Chong S
- Teng K
- Becht E
- Chen J
- Sieow J
- Penny H
- Ching G
- Devi S
- Adrover J
- Li J
- Liong K
- Tan L
- Poon Z
- Foo S
- Chua J
- Su I
- Balabanian K
- Bachelerie F
- Biswas S
- Larbi A
- Hwang W
- Madan V
- Koeffler H
- Wong S
- Newell E
- Hidalgo A
- Ginhoux F
- Ng L
- Publication year
- Publication venue
- Immunity
External Links
Snippet
Neutrophils are specialized innate cells that require constant replenishment from proliferative bone marrow (BM) precursors as a result of their short half-life. Although it is established that neutrophils are derived from the granulocyte-macrophage progenitor …
- 210000000440 Neutrophils 0 title abstract description 199
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Hybridisation probes
- C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Evrard et al. | Developmental analysis of bone marrow neutrophils reveals populations specialized in expansion, trafficking, and effector functions | |
Tikhonova et al. | The bone marrow microenvironment at single-cell resolution | |
Casanova-Acebes et al. | Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells | |
Alam et al. | Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer | |
Asada et al. | Differential cytokine contributions of perivascular haematopoietic stem cell niches | |
Werner et al. | Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke | |
Bonnardel et al. | Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche | |
Li et al. | Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy | |
Dutta et al. | Myocardial infarction activates CCR2+ hematopoietic stem and progenitor cells | |
Calcagno et al. | The myeloid type I interferon response to myocardial infarction begins in bone marrow and is regulated by Nrf2-activated macrophages | |
Riedel et al. | Tumor-induced stromal reprogramming drives lymph node transformation | |
Zhang et al. | IL-6 blockade reverses bone marrow failure induced by human acute myeloid leukemia | |
Kunisaki et al. | Arteriolar niches maintain haematopoietic stem cell quiescence | |
LaMarche et al. | An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis | |
Satake et al. | C/EBPβ is involved in the amplification of early granulocyte precursors during candidemia-induced “emergency” granulopoiesis | |
Sahakian et al. | Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology | |
Stengel et al. | Peritoneal level of CD206 associates with mortality and an inflammatory macrophage phenotype in patients with decompensated cirrhosis and spontaneous bacterial peritonitis | |
Zhou et al. | Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration | |
US20210123021A1 (en) | Neutrophil subtypes | |
Pick et al. | Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis | |
Louka et al. | Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia | |
McDowell et al. | Obesity alters monocyte developmental trajectories to enhance metastasis | |
Nie et al. | A YAP/TAZ-CD54 axis is required for CXCR2− CD44− tumor-specific neutrophils to suppress gastric cancer | |
Shang et al. | R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization | |
Gerber-Ferder et al. | Breast cancer remotely imposes a myeloid bias on haematopoietic stem cells by reprogramming the bone marrow niche |