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Keenan et al., 2024 - Google Patents

How URAT1 inhibitors can shape the future of chronic gout treatment: a narrative review of uricosurics past and present

Keenan et al., 2024

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Document ID
4337428321348128337
Author
Keenan R
Shen Z
Yan S
Yeh L
Pillinger M
Publication year

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Snippet

Gout is a common inflammatory arthritis preceded by chronically elevated levels of serum urate. In addition to leading to gouty flares, hyperuricemia can result in stone-like deposits of monosodium urate crystals (tophi) being deposited in joints and soft tissue, where they …
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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