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Xie et al., 2007 - Google Patents

Improving simvastatin bioconversion in Escherichia coli by deletion of bioH

Xie et al., 2007

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Document ID
4327168605585650333
Author
Xie X
Wong W
Tang Y
Publication year
Publication venue
Metabolic Engineering

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Simvastatin is an important cholesterol lowering compound and is currently synthesized from the natural product lovastatin via multistep chemical synthesis. We have previously reported the use of an Escherichia coli strain BL21 (DE3)/pAW31 as the host for whole-cell …
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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    • C12P7/6445—Glycerides
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