[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Dinarello, 2019 - Google Patents

The IL-1 family of cytokines and receptors in rheumatic diseases

Dinarello, 2019

Document ID
4313319445457970599
Author
Dinarello C
Publication year
Publication venue
Nature Reviews Rheumatology

External Links

Snippet

More than any other cytokine family, the 11 members of the IL-1 family are associated with innate immune responses, which occur in acute inflammation and chronic inflammatory conditions such as rheumatic diseases. In many rheumatic diseases, the severity of the …
Continue reading at www.nature.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00

Similar Documents

Publication Publication Date Title
Dinarello The IL-1 family of cytokines and receptors in rheumatic diseases
Bertheloot et al. HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins
Holzinger et al. Alarmins of the S100-family in juvenile autoimmune and auto-inflammatory diseases
Ji et al. Critical roles for interleukin 1 and tumor necrosis factor α in antibody-induced arthritis
Moltó et al. Anti-IL-1 molecules: new comers and new indications
US10940126B2 (en) Inhibition of IL-8 in the treatment of pain and/or bone loss
US20090142806A1 (en) Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor
EP1743648A1 (en) Method for treating inflammation
Harel et al. Balance between Interleukin-18 and Interleukin-18 binding protein in auto-inflammatory diseases
AU2005277236A1 (en) Methods and compositions for treating allergic inflammation
Hernandez‐Santana et al. Current perspectives on the interleukin‐1 family as targets for inflammatory disease
Wang et al. Interleukin-18 and IL-18BP in inflammatory dermatological diseases
CA2754945C (en) Peptides and sirna for modulating inflammation
Yang et al. Interleukin-9 aggravates isoproterenol-induced heart failure by activating signal transducer and activator of transcription 3 signalling
US20200255825A1 (en) Biological materials and therapeutic uses thereof
Lavric et al. Alarmins firing arthritis: helpful diagnostic tools and promising therapeutic targets
Galozzi et al. Development and role in therapy of canakinumab in adult-onset Still’s disease
Yuan IL-33 in autoimmunity; possible therapeutic target
Ouyang et al. Potential mechanistic roles of Interleukin-33 in rheumatoid arthritis
EP3316886B1 (en) Methods and compounds for the alleviation and/or prevention of pain
TW202106712A (en) Methods of diagnosis and treatment of rheumatoid arthritis
WO2013070563A1 (en) Treatment of autoimmune and inflammatory disorders by inhibition of blimp-1
Crofford The role of COX-2 in rheumatoid arthritis synovial tissues
Dumont The interleukin-1 families of cytokines and receptors: therapeutic potential for immunomodulation and the treatment of inflammatory disorders
Kevin et al. IL-23 in arthritic and inflammatory pain development in mice