Jetton et al., 1994 - Google Patents
Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut.Jetton et al., 1994
View HTML- Document ID
- 4303978694372214903
- Author
- Jetton T
- Liang Y
- Pettepher C
- Zimmerman E
- Cox F
- Horvath K
- Matschinsky F
- Magnuson M
- Publication year
- Publication venue
- Journal of Biological Chemistry
External Links
Snippet
A transgene consisting of an upstream glucokinase (GK) promoter fragment linked to coding sequences of the human growth hormone gene was expressed in certain neuroendocrine cells of the pancreas, pituitary, brain, gut, thyroid, and lungs of mice. In pancreas, the …
- 210000004556 Brain 0 title abstract description 83
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Hybridisation probes
- C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Jetton et al. | Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. | |
| McLean et al. | Revisiting the complexity of GLP-1 action from sites of synthesis to receptor activation | |
| Jurek et al. | The oxytocin receptor: from intracellular signaling to behavior | |
| Naveilhan et al. | Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor | |
| Jonsson et al. | Insulin-promoter-factor 1 is required for pancreas development in mice | |
| Alpert et al. | Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons | |
| Wierup et al. | CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight | |
| Asa et al. | The pathogenesis of pituitary tumours | |
| Luuk et al. | Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome | |
| Wang et al. | Fluorescent labeling of both GABAergic and glycinergic neurons in vesicular GABA transporter (VGAT)–Venus transgenic mouse | |
| Cawley et al. | New roles of carboxypeptidase E in endocrine and neural function and cancer | |
| Kitamura et al. | Preserved pancreatic β-cell development and function in mice lacking the insulin receptor-related receptor | |
| Dowling et al. | Acute changes in maternal thyroid hormone induce rapid and transient changes in gene expression in fetal rat brain | |
| US5880261A (en) | Transcription factor Islet-Brain 1 (IB1) | |
| Weinert et al. | Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration | |
| Stohn et al. | Cthrc1, a novel circulating hormone regulating metabolism | |
| US7815895B2 (en) | Method for activating efferent sympathetic nerves innervating adipose tissues to improve obesity and symptoms associated therewith | |
| Zhang et al. | Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons | |
| Thompson et al. | Widespread expression of ErbB2, ErbB3 and ErbB4 in non-human primate brain | |
| Chachlaki et al. | NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice | |
| Meier et al. | Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing | |
| Kato et al. | Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in pancreatic beta cells. Evidence for improved glucose tolerance and enhanced insulin secretion by VIP and PHM-27 in vivo. | |
| Maj et al. | Novel insights into the distribution and functional aspects of the calcium binding protein secretagogin from studies on rat brain and primary neuronal cell culture | |
| Counts et al. | Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease | |
| Tan et al. | Distribution of corticotropin‐releasing factor (CRF) receptor binding in the mouse brain using a new, high‐affinity radioligand,[125I]‐PD‐Sauvagine |