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Bagade et al., 2022 - Google Patents

Enhancement of Permeation Rate of Rifabutin Using Encapsulation of Lipid-Based Nanoparticles through Chicken Ileum by Statistical Optimization Approach

Bagade et al., 2022

Document ID
4306669388940001876
Author
Bagade O
Doke-Bagade P
Publication year
Publication venue
Innovations in Green Nanoscience and Nanotechnology

External Links

Snippet

Solid lipid nanoparticles loaded with rifabutin are ideal candidates for use in treating HIV patients. In this chapter, RBT lipid nanoparticles are formulated using a 32 full factorial design and the resulting optimum formulation is evaluated and described. In HIV (human …
Continue reading at www.taylorfrancis.com (other versions)

Classifications

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    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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