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Wu et al., 2011 - Google Patents

Preparation of ethyl 3R, 5S-6-(benzyloxy)-3, 5-dihydroxy-hexanoate by recombinant diketoreductase in a biphasic system

Wu et al., 2011

Document ID
4211835166239197313
Author
Wu X
Chen C
Liu N
Chen Y
Publication year
Publication venue
Bioresource technology

External Links

Snippet

Diketoreductase from Acinetobacter baylyi ATCC 33305 is a unique carbonyl reductase, which can stereoselectively reduce ethyl-6-(benzyloxy)-3, 5-dioxohexanoate to ethyl 3R, 5S- 6-(benzyloxy)-3, 5-dihydroxy-hexanoate, an advanced intermediate for statin drugs. In the …
Continue reading at www.sciencedirect.com (other versions)

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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
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    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
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    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
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    • C12P7/16—Butanols
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    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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