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Gemcitabine induced myositis in patients with pancreatic cancer: case reports and topic review

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Abstract

Gemcitabine potential myotoxicity has been described in several cases of radiation recall and in patients treated with gemcitabine alone or in combination with other chemotherapy agents. We report two cases of gemcitabine related myositis identified at our institution, and perform a literature review of cases which meet the criteria for gemcitabine induced myositis associated to either radiation therapy or chemotherapy alone.

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Acknowledgments

We thank Dr Jerome B. Posner for his advice and extremely valuable suggestions. We thank Judith Lampron for her editorial assistance.

Conflict of interest

The authors report no relevant conflict of interest

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Authors and Affiliations

  1. Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA

    Elena Pentsova, Xi Chen & Adília Hormigo

  2. Department of Neurology and Neuroscience, Weill Cornell College of Medicine of Cornell University, New York, NY, USA

    Anli Liu

  3. Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA

    Marc Rosenblum

  4. Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA

    Eileen O’Reilly

Authors
  1. Elena Pentsova
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  2. Anli Liu
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  4. Eileen O’Reilly
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  5. Xi Chen
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  6. Adília Hormigo
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Corresponding author

Correspondence to Adília Hormigo.

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Pentsova, E., Liu, A., Rosenblum, M. et al. Gemcitabine induced myositis in patients with pancreatic cancer: case reports and topic review. J Neurooncol 106, 15–21 (2012). https://doi.org/10.1007/s11060-011-0672-8

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  • DOI: https://doi.org/10.1007/s11060-011-0672-8

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