Overview
- Editors:
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Joyce W. Lustbader
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Irving Center for Clinical Research Columbia University College of Physicians and Surgeons, New York, USA
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David Puett
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Department of Biochemistry, University of Georgia, Athens, USA
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Raymond W. Ruddon
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Eppley Institute for Research, University of Nebraska Medical Center, Omaha, USA
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About this book
Advances in the field of glycoprotein hormones necessitated a second international symposium on this topic, held March 11 to 14, 1993, in Santa Barbara, California, and again sponsored by Serono Symposia, USA. The meeting was twofold in its concept: (1) the dissemination of the current research in the field and (2) honoring three scientists who have greatly contributed to this field, Drs. Harold Papkoff, Robert Ryan, and Darrell Ward, upon their retirements. We were honored to have Dr. John Pierre present as a participant at the meeting and also serving as master of ceremonies at the banquet. Certainly one of the highlights at the first meeting, held in 1989, was the cloning of the CG/LH receptor. This second meeting was also filled with insightful and innovative scientific presentations. Significant advances in the regulation of gene transcription of the gonadotropins were presented by Pamela Mellon, James Hoeffler, John Nilson, Bruce Weintraub, and Joel Habener. These presentations reflected major advances from the in the understanding concepts offered at the last meeting. Other advances of hormone structure/function included the continuing work by Joyce Lustbader on the determination of the three-dimensional structure of hCG, including a new approach using nonisotopic labels for 3-D and 4-D NMR imaging. New insights into biosynthesis of hCG were proposed by Irving Boime. Studies directed at identifying receptor contact regions were presented by Henry Keutmann and David Puett.
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Article
Open access
20 October 2020
Table of contents (24 papers)
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Reflections Past and Present
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Regulation of Gene Expression
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- C. M. Clay, R. A. Keri, D. L. Hamernik, L. L. Heckert, J. H. Nilson
Pages 19-35
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- Pamela L. Mellon, David J. Steger, Friedemann Horn, Kerry M. Barnhart, Marita Büscher, Claudia Stauber et al.
Pages 36-43
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- Stephen M. Jackson, Kerry M. Barnhart, Pamela L. Mellon, Arthur Gutierrez-Hartmann, James P. Hoeffler
Pages 44-64
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- Joel F. Habener, Terry E. Meyer
Pages 65-74
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- Bruce D. Weintraub, Myung K. Kim, Donald L. Bodenner, N. Rao Thotakura, Mariusz W. Szkudlinski, Lata Joshi et al.
Pages 75-78
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Hormonal Protein Structure/Function
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- Joyce W. Lustbader, Chuan Wang, Xiaolu Zhang, Steven Birken, Hao Wu, Jonathan Miles Brown et al.
Pages 81-102
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- Masaki Bo, Brian L. Strauss, Irving Boime
Pages 118-121
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- David Puett, Jianing Huang, Haiying Xia
Pages 122-134
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Protein Processing and Posttranslational Events
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Front Matter
Pages 135-135
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- Raymond W. Ruddon, Jeffrey R. Huth, Elliott Bedows, Kimberly Mountjoy, Fulvio Perini
Pages 137-155
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Editors and Affiliations
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Irving Center for Clinical Research Columbia University College of Physicians and Surgeons, New York, USA
Joyce W. Lustbader
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Department of Biochemistry, University of Georgia, Athens, USA
David Puett
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Eppley Institute for Research, University of Nebraska Medical Center, Omaha, USA
Raymond W. Ruddon