Igniting Discovery in Alzheimer’s Research

Taking on one of the toughest diseases

Six million Americans are living with Alzheimer’s Disease, and that number is projected to soar to 14 million by 2050.

At the Keck School of Medicine, we have four world-renowned research centers dedicated to combating this devastating disease. Our approach spans from basic research on early molecular changes leading to cognitive decline to landmark clinical trials. We study how to enhance the effectiveness of new anti-amyloid compounds, test anti-tau treatments, and aim to prevent Alzheimer’s disease. Leading in open science, our work provides researchers with a wealth of new information. The Keck School of Medicine is poised to be at the forefront of Alzheimer’s prevention within the next ten years.

Screen grab of Alzheimer's overview video. A hand pointing at a screen

Leading the Charge on New Treatments: The Alzheimer’s Therapeutic Research Institute at USC

The Alzheimer’s Therapeutic Research Institute (ATRI) at USC is at the forefront of bringing effective new treatments for Alzheimer’s disease to the world through rigorous clinical trial design and the identification of reliable biomarkers for early detection of the disease – long before cognitive decline occurs.

Accelerating Discovery: The USC Mark and Mary Stevens Neuroimaging and Informatics Institute

With cutting-edge imaging and information technologies, and one of the largest global data networks in the world, the USC Mark and Mary Stevens Neuroimaging and Informatics Institute is accelerating the pace of discovery in Alzheimer’s disease by leveraging imaging and big data to reveal what was impossible to perceive before.

Video screen shot of Dean Carolyn Meltzer

Cutting-Edge Alzheimer’s Research and Care: USC Neurology/Alzheimer’s Disease Research Center

In the hunt for innovative treatments for Alzheimer’s disease, the Keck School of Medicine of USC’s Department of Neurology, home to the USC’s Alzheimer’s Disease Research Center, is working to bring the latest discoveries to patients and their families.

Targeting the Earliest Signs of Alzheimer’s Disease: The Zilkha Neurogenetic Institute

The Zilkha Neurogenetic Institute is pursuing new treatments for Alzheimer’s disease that could stop the disease process long before cognitive decline begins – treatments which would target early problems in the brain’s vascular system that may lead to dementia.

Alzheimer’s Disease Research Center

The Alzheimer Disease Research Center at USC (ADRC) works to understand the biological changes that may precede worsening memory and to assess whether new treatments, including drugs, may be helpful in preventing memory or delay memory loss.

Alzheimer’s Therapeutic Research Institute

The mission of the Alzheimer’s Therapeutic Research Institute (ATRI) is to rigorously test methods for early detection of, and treatments for Alzheimer’s disease (AD) and bring effective therapeutics to the world.

Neuroimaging and Informatics Institute

USC’s Mark and Mary Stevens Neuroimaging and Informatics Institute (USC Stevens INI) applies innovative imaging and information technologies to the study of the brain. We share our data and resources with thousands of collaborators around the world.

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USC Center for Personalized Brain Health

The USC Center for Personalized Brain Health focuses on preventing Alzheimer’s disease by targeting the APOE gene and the roles of fatty acids in the brain, translating scientific discoveries into personalized prevention strategies. The center brings together experts from various disciplines to create a roadmap for personalized brain health and reduce Alzheimer’s genetic risk.

Illustration of DNA and silhouettes of people

Zilkha Neurogenetic Institute at USC

The Zilkha Neurogenetic Institute (ZNI) is a cross-disciplinary hub for the neuroscience community at USC. At Zilkha, we conduct world-class science in state-of-the-art labs.

Educational Programs

The Keck School of Mecidine offers an inter-campus PhD in medical biophysics (MBPH) that includes faculty from all over USC who not only have active biophysical research programs and serve as mentors, but also contribute to courses offered by the program. Meanwhile, the MS in Neuroimaging and Informatics, at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute, is a premier one-year degree program on brain imaging and the associated informatics.

PhD in Medical Biophysics

MS in Neuroimaging and Informatics