Testosterone

Testosterone
type of chemical entity (en)
Bayanai
Ƙaramin ɓangare na	androstane steroid (en)
Amfani	magani
Mai ganowa ko mai ƙirƙira	János Freud (en) da Ernst Laqueur (mul)
Stereoisomer of (en)	epitestosterone (en)
Sinadaran dabara	C₁₉H₂₈O₂
Canonical SMILES (en)	CC12CCC3C(C1CCC2O)CCC4=CC(=O)CCC34C
Isomeric SMILES (en)	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
World Health Organisation international non-proprietary name (en)	testosterone
Legal status (medicine) (en)	boxed warning (en)
Subject has role (en)	androgen (en) , carcinogen (en) da primary metabolite (en)
NCI Thesaurus ID (en)	C862

Testosterone^[1] Testosterone shine farkon hormone na jima'i na maza da kuma steroid na anabolic a cikin maza. A cikin mutane, testosterone^[2] yana taka muhimmiyar rawa wajen haɓaka naman haifuwa na maza kamar gwaji da prostate, da kuma haɓaka halayen jima'i na biyu kamar ƙara yawan tsoka da ƙwayar ƙashi, da haɓaka gashin jiki. Yana da alaƙa da ƙara tashin hankali, tashin hankali, da dabi'a na laifi, sha'awar jima'i, sha'awar burge abokan tarayya da sauran halayen shari'a.^[3]

Bugu da ƙari, testosterone^[4] a cikin jinsi biyu yana shiga cikin lafiya da jin daɗin rayuwa, inda yake da tasiri mai mahimmanci akan yanayin gabaɗaya, fahimta, halayen zamantakewa da jima'i, metabolism da fitarwar kuzari, tsarin zuciya da jijiyoyin jini, da kuma rigakafin osteoporosis.^[5] Rashin isassun matakan testosterone a cikin maza na iya haifar da rashin daidaituwa ciki har da rauni, tara ƙwayoyin adipose mai a cikin jiki, damuwa da damuwa, batutuwan yin jima'i, da asarar kashi.^[6]

Gabaɗaya, androgens irin su testosterone suna haɓaka haɓakar furotin kuma don haka haɓakar kyallen takarda tare da masu karɓar androgen . ^[7] Kwanan nan, Gharahdaghi et al. ya ba da rahoton cewa testosterone na endogenous da exogenous suna taka rawar da ta dace wajen daidaitawa don horar da motsa jiki a cikin samari da mazan maza. ^[8] Ana iya kwatanta Testosterone a matsayin ciwon virilising da anabolic effects (ko da yake waɗannan nau'o'in kwatancen suna da ɗan sabani, kamar yadda akwai babban haɗin gwiwa tsakanin su). ^[9]

Hakanan za'a iya rarraba tasirin Testosterone ta shekarun faruwar al'ada. Don tasirin bayan haihuwa a cikin maza da mata, waɗannan galibi sun dogara ne akan matakan da tsawon lokacin watsawar testosterone kyauta

Abubuwan da ke faruwa kafin haihuwa sun kasu kashi biyu, an rarraba su dangane da matakan ci gaba. Lokacin farko yana faruwa tsakanin makonni 4 zuwa 6 na ciki. Misalai sun haɗa da ɓarkewar al'aura kamar haɗaɗɗen layin tsakiya, urethra phallic, ɓacin rai da rugujewa, da haɓaka phallic ; ko da yake aikin testosterone ya yi ƙasa da na dihydrotestosterone . Har ila yau, akwai ci gaban prostate gland da kuma seminal vesicles.

A cikin uku na biyu, matakin androgen yana haɗuwa da samuwar jima'i . ^[10] Musamman, testosterone, tare da anti-Müllerian hormone (AMH) suna inganta haɓakar ƙwayar Wolffian da lalatawar ƙwayar Müllerian bi da bi. Wannan lokacin yana rinjayar mace ko namiji na tayin kuma zai iya zama mafi kyawun tsinkaya game da dabi'un mata ko na namiji kamar nau'in jima'i fiye da matakan babba. Androgens na haihuwa a fili suna tasiri sha'awa da shiga cikin ayyukan jinsi kuma suna da matsakaicin tasiri akan iyawar sararin samaniya. Daga cikin matan da ke da hyperplasia na adrenal na haihuwa, wasan kwaikwayo na maza a cikin yara yana da alaƙa da rage gamsuwa da jinsin mata da rage sha'awar jima'i a cikin girma. ^[11]

1. ↑ https://en.m.wikipedia.org/wiki/Testosterone
2. ↑ https://www.urologyhealth.org/urology-a-z/l/low-testosterone
3. ↑ https://www.health.harvard.edu/staying-healthy/testosterone--what-it-does-and-doesnt-do
4. ↑ https://www.yourhormones.info/hormones/testosterone/
5. ↑ https://www.ncbi.nlm.nih.gov/books/NBK526128/
6. ↑ https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/testosterone-therapy/art-20045728
7. ↑ Empty citation (help)
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9. ↑ Empty citation (help)
10. ↑ Empty citation (help)
11. ↑ Empty citation (help)