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Code for reproducing the analysis in Gavish et al. "The transcriptional hallmarks of intra-tumor heterogeneity across a thousand tumors".

R 110 14 Updated Sep 6, 2024

Toolkit for single-cell copy number analysis

R 23 4 Updated Oct 15, 2024

Nextflow pipeline to preprocess perturb-seq/MAESTER data.

Python 1 Updated Mar 13, 2025

LuLu is the free open-source macOS firewall

Objective-C 10,880 501 Updated Apr 17, 2025

MiTo: MT-SNVs based single-cell lineage tracing in python

Python 2 Updated Apr 24, 2025
Jupyter Notebook 4 1 Updated Jul 15, 2024

Estimating tumor fraction in cell-free DNA from ultra-low-pass whole genome sequencing.

R 182 87 Updated Mar 20, 2024

SIB course on single cell transcriptomics by mostly using the Seurat pipeline

R 82 36 Updated Mar 12, 2025

Single cell RNA sequencing analysis course

HTML 214 104 Updated Apr 10, 2025
R 2 Updated Feb 12, 2025

Count bases in BAM/CRAM files

CMake 316 97 Updated Jan 31, 2022

accessory scripts for processing varscan somatic/copynumber outputs.

Python 9 10 Updated Dec 8, 2017

bam-readcount parser

Python 2 1 Updated Oct 15, 2021

A set of tools to annotate VCF files with expression and readcount data

Python 29 13 Updated Mar 4, 2025

Platypus Variant Caller

Python 108 38 Updated Jun 27, 2024
Perl 7 9 Updated Apr 27, 2022

Variant calling and somatic mutation/CNV detection for next-generation sequencing data

159 34 Updated Mar 28, 2023

Application for making ENCODE Blacklists

C++ 306 40 Updated Apr 23, 2021
Shell 14 15 Updated Mar 6, 2024

Genome Data Analytics (DSSC 2021)

HTML 5 2 Updated Jun 5, 2021

Extracting mutational signatures via LASSO. The manuscript of the method is published on PLOS Computational Biology and available at: https://journals.plos.org/ploscompbiol/article?id=10.1371/journ…

R 11 4 Updated Apr 18, 2025

FInding REliable Variants without ArTifacts

HTML 22 8 Updated Nov 18, 2022
Jupyter Notebook 3 Updated Mar 2, 2025

cython + htslib == fast VCF and BCF processing

Cython 396 73 Updated Sep 16, 2024

A Variant Call Format reader for Python.

Python 413 198 Updated Sep 22, 2023

This repository was used to contain the tutorials of telemere length calculation for single cell DNA-seq data.

HTML 3 Updated Oct 12, 2023

Telomerecat: The telomere computational analysis tool

Python 21 5 Updated Aug 4, 2021
Python 11 2 Updated Apr 13, 2020
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