Annotation of VCF variants with functional impact and from databases (executable+library)

Genomic VCF to tab-separated values

VarFish: comprehensive DNA variant analysis for diagnostics and research

VEP-like tool for sequence ontology and HGVS annotation of VCF files

A port of biocommons/hgvs to the Rust programming language

Genome annotation based on Rust and RocksDB

Filter a VCF to discard false positive variants

(Legacy) Annotate variants for import into VarFish server.

A collection of software to work with genomic variants

Setup VarFish as using Docker Compose

A port of biocommons/seqrepo to the Rust programming language

R script to 1) Extract missense variants that had been observed in "clinical testing" (as opposed to "literature only") in ClinVar. 2) Calculating movability and reappearance parameters using the aggregated and capped Invitae variant counts. 3) Apply the movability and reappearance parameters to ClinVar genes, calculating their movability- and r…

Collection of expressions that can be used in slivar

Download public databases for VarFish

VarFish REST API client (CLI + Python package)

Rust-based background worker for varfish-server

Filtering vcf with population gvcf

Simple REST API wrapper for CADD-scripts

multi-anchors filtering and multi-threads implementation for vcf filtering

VarFish (Snakemake) Client Workflow for Querying Snakemake