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Theta activity in the dorsal pathway predicts working memory

Project ID
TDW

Expected experimentation period
Start date: 31/10/2019 End date: 10/03/2020

Experimental location
Montreal Neurological Institute, McGill University, Montreal, QC

Task Description
The auditory working memory task administered during the screening test and throughout the 7 experimental sessions involved the mental manipulation of the order of three pure tones and is depicted in Figure 1A. In each 15-s trial, a sequence of three tones was presented, followed by a silent retention period of 3800 ms. A visual cue then appeared on the screen, consisting of the numbers 1, 2, and 3 in variable order. The order of these numbers corresponded to the order of tones in a reordered target sequence. For example, the visual cue “312” instructed participants to reorder the sequence of the original tones (say, A-B-C) such that the third tone now came first, that is, C-A- B. Finally, after 5 s participants were presented with a second tone sequence and indicated by left or right click on a mouse whether it was a ‘match’ or ‘mismatch’ to the target sequence, that is, the correct manipulation of the encoded sequence. At the end of each trial, visual feedback indicated whether the response was correct.

Participant categories
We retained 18 neurologically healthy young adults (8 women; mean age of 22 years, ranging from 18 to 29 years) to participate in our study after screening (see below). All participants were right-handed and reported normal hearing and no history of neurological disease. Nine participants had some musical training, with an average duration of 2.5 years and no participant having more than 4 years of training.

Trigger channels
n/a

Events

  1. Mk
  2. S128

Primary Publications
Whittaker HT, Khayyat L, Fortier-Lavallée J, Laverdière M, Bélanger C, Zatorre RJ and Albouy P (2024) Information-based rhythmic transcranial magnetic stimulation to accelerate learning during auditory working memory training: a proof-of-concept study. Front. Neurosci. 18:1355565. doi: https://doi.org/10.3389/fnins.2024.1355565

Acknowledgements
Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, Healthy Brains for Healthy Lives initiative of McGill University, Brain Canada, Fonds de recherche du Québec - Santé

Contact Person
Philippe Albouy: philippe.albouy@psy.ulaval.ca
Corentin Labelle: corentin.labelle.1@ulaval.ca

Data dissemination and standardization supported by EEGNet.Loris.ca

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