Add CCFv3a-BBP blog #339
Add CCFv3a-BBP blog #339
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docs/source/blog/CCFv3BBP.md
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| [Piluso et al., 2025](https://doi.org/10.1162/imag_a_00565) recently published an extended and improved Common Coordinate Framework atlas version of the entire mouse brain, called CCFv3BBP or CCFv3a extended. While the previous [CCFv2 and CCFv3](https://doi.org/10.1016/j.cell.2020.04.007) atlas versions from the Allen Institute for Brain Science (AIBS) have been widely adopted by the neuroscience community, they retained certain limitations. The updated framework addresses these by incorporating the most rostral and caudal parts of the brain, resulting in a non-truncated main olfactory bulb, cerebellum, and medulla (CCFv3a), features absent or truncated in earlier versions. Additionally, the cerebellum annotation now includes the granular, molecular, and Purkinje cell layers. This new version also incorporates a high resolution (10 µm isotropic) Nissl-stained volume precisely aligned in the CCFv3a and also extended at the entire mouse brain level. | ||
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| Building on this new data, a population-based average Nissl template was constructed from 86,901 coronal Nissl-stained slices, derived from 734 postnatal day 56 C57BL/6J mouse brains from the [AIBS in situ hybridization data portal](https://www.nature.com/articles/nature05453). |
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a high resolution (10 µm isotropic) Nissl-stained volume precisely aligned in the CCFv3a and also extended at the entire mouse brain level.
Building on this new data, a population-based average Nissl template
IIUC "The Nissl-stained volume" and "a population-based average Nissl template" are the same thing, right?
So maybe we should change to "this population-based average Nissl template" to clarify?
But I don't understand what "this new data" is? The additional annotations?
Also, unsure about prepositions "aligned in" and "extended at" but I will let a native speaker decide - that part is clear to me.
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I see maybe its unclear. Theres 2 volumes a single animal nissl and population average nissl. I'll edit it tomorrow and standardise the terminology.
I'll also try to be a bit more clear about what's new about this (explaining whats extended vs how its been aligned, etc).
Co-authored-by: Alessandro Felder <alessandrofelder@users.noreply.github.com>
Adds a new blog for the CCFv3BBP atlas by Sébastien Piluso & @PolarBean.