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OBO Database Ingestion

DOI

This repository shows how databases can be formalized as an OBO Ontology in the OBO flat file format, OWL format, and OBO Graph JSON format. A list of the databases whose controlled vocabularies and related content can be readily converted to OBO can be in found in the PyOBO source code's sources/ folder here.

Further discussion:

Contents

Each resource gets a subdirectory in the export/ directory containing the following exports:

A manifest of all resources is available at manifest.yml.

Build

To generate OBO files, run the following shell commands (Python 3.8+):

$ uv tool install tox --with tox-uv
$ tox

PURLs

See PURL configuration at https://github.com/perma-id/w3id.org/tree/master/biopragmatics. This W3ID entry makes ontology artifacts in the "export" folder (https://github.com/biopragmatics/obo-db-ingest/tree/main/export) resolvable. Here are a few examples:

Resource Version Type Example PURL
Reactome Sequential https://w3id.org/biopragmatics/resources/reactome/83/reactome.obo
Interpro Major/Minor https://w3id.org/biopragmatics/resources/interpro/92.0/interpro.obo
DrugBank Salt Semantic https://w3id.org/biopragmatics/resources/drugbank.salt/5.1.9/drugbank.salt.obo
MeSH Year https://w3id.org/biopragmatics/resources/mesh/2003/mesh.obo.gz
UniProt Year/Month https://w3id.org/biopragmatics/resources/uniprot/2022_05/uniprot.obo.gz
HGNC Date https://w3id.org/biopragmatics/resources/hgnc/2023-02-01/hgnc.obo
CGNC unversioned https://w3id.org/biopragmatics/resources/cgnc/cgnc.obo

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🗄️ Conversion of biomedical nomenclatures like HGNC to OBO

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