[go: up one dir, main page]
More Web Proxy on the site http://driver.im/
Skip to content
This repository has been archived by the owner on Feb 18, 2023. It is now read-only.
/ GBKviz Public archive

Easy-to-use web application for visualization and comparison of genomes in Genbank file

License

Notifications You must be signed in to change notification settings

moshi4/GBKviz

Repository files navigation

GBKviz: Genbank Data Visualization WebApp

Open in Streamlit Python3 License Latest PyPI version

Table of contents

Overview

GBKviz is a web-based Genbank data visualization and comparison tool developed with streamlit web framework. GBKviz allows user to easily and flexibly draw CDSs in user-specified genomic region (PNG or SVG format is available). It also supports drawing genome comparison results by MUMmer. This software is developed under the strong inspiration of EasyFig.

GBKviz Demo GIF
Click here to try GBKviz on Streamlit Cloud.

⚠️ Due to the limited resources in Streamlit Cloud, it may be unstable.

Install

GBKviz is implemented in Python3 (Tested on Ubuntu20.04)

Install PyPI stable version with pip:

pip install gbkviz

If you want to enable genome comparison in GBKviz, MUMmer is required.

Install MUMmer with apt command (Ubuntu):

sudo apt install mummer

Dependencies

  • Streamlit
    Simple web framework for data analysis

  • BioPython
    Utility tools for computational molecular biology

  • MUMmer
    Genome alignment tool for comparative genomics

Command Usage

Launch GBKviz in web browser (http://localhost:8501):

gbkviz_webapp

Genome Comparison

In GBKviz, MUMmer is used as genome comparison tool.
Following four genome comparison methods are available.

  • Nucleotide One-to-One Mapping
  • Nucleotide Many-to-Many Mapping
  • Protein One-to-One Mapping
  • Protein Many-to-Many Mapping

User can download and check genome comparison results file.
Genome comparison results file is in the following tsv format.

Columns Contents
REF_START Reference genome alignment start position
REF_END Reference genome alignment end position
QUERY_START Query genome alignment start position
QUERY_END Query genome alignment end position
REF_LENGTH Reference genome alignment length
QUERY_LENGTH Query genome alignment length
IDENTITY Reference and query genome alignment identity (%)
REF_NAME Reference genome name tag
QUERY_NAME Query genome name tag