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COCOA-Tree: COllaborative COevolution Analysis Toolbox

COCOA-Tree is a Python library to perform coevolution analyses of proteins and integrate phylogenetic information to better understand the coevolution signals.

It regroups various coevolution metrics and corrections, such as statistical coevolution analysis (SCA) or mutual information (MI).

Website: tree-bioinfo-intra.timc.fr/projects/cocoa/

Library organization

COCOA-Tree is organized in several modules, each allowing to perform different tasks of a coevolution analysis pipeline:

cocoatree_orga

Installation

Dependencies

COCOA-Tree requires:

  • Python (>= 3.9)
  • NumPy
  • scikit-learn
  • biopython
  • ete3

Matplotlib is also required for running the examples.

User installation

To install for development purposes, use::

python setup.py develop

All changes in the python module will be repercuted on the installed version (in practice the installed version is a symlink towards the package in development).

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