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(Windows) AMDock: Assisted molecular docking with AutoDock4 and AutoDockVina

Python 67 22 Updated Aug 1, 2022
Jupyter Notebook 264 36 Updated Mar 18, 2024

GNN trained to predict changes in thermodynamic stability for protein point mutants

Python 173 32 Updated Feb 14, 2025

an efficient distributed PyTorch framework

Python 137 39 Updated May 10, 2025

Official Repository for the Uni-Mol Series Methods

Python 887 142 Updated May 29, 2025

Refactored for Compatibility with Amber20

Shell 6 Updated Nov 20, 2024

FEP-SPell-ABFE: An Open Source Alchemical Absolute Binding Free Energy Calculation Workflow for Drug Discovery

Python 66 12 Updated Jan 8, 2025

PRnet is a flexible and scalable perturbation-conditioned generative model predicting transcriptional responses to unseen complex perturbations at bulk and single-cell levels.

Jupyter Notebook 52 7 Updated Dec 13, 2024

[IJCAI 2023 survey track]A curated list of resources for chemical pre-trained models

526 56 Updated Jun 17, 2023

Scripts for virtual screening, cross docking and protein relax using Schrödinegr and Rosetta

Shell 76 23 Updated Apr 11, 2025

Open-Source Quantum Chemistry – an electronic structure package in C++ driven by Python

C++ 1,061 462 Updated Jun 20, 2025

psi4+RDKit

Python 101 22 Updated May 13, 2025

DockQ is a single continuous quality measure for Protein, Nucleic Acids and Small Molecule Docking Models

Python 287 63 Updated Jan 23, 2025

Code for ColabDock paper

Python 141 20 Updated May 1, 2025

Weighted Ensemble simulation framework in Python

Python 56 20 Updated Jun 12, 2025

FreeSASA Python Module

Cython 54 14 Updated Nov 15, 2023

Workflow to clean up and fix structural problems in protein-ligand binding datasets

Jupyter Notebook 46 7 Updated May 7, 2025

Protein-Ligand Interaction Profiler - Analyze and visualize non-covalent protein-ligand interactions in PDB files according to 📝 Adasme et al. (2021), https://doi.org/10.1093/nar/gkab294

Python 547 119 Updated Jun 20, 2025
Python 1 Updated Oct 15, 2024

Open source code for AlphaFold 2.

Python 13,609 2,420 Updated Mar 18, 2025

Official repository for the Boltz biomolecular interaction models

Python 67B1 2,906 444 Updated Jun 21, 2025

Dock organometallic compounds to proteins/DNA/biomolecules

Python 16 7 Updated May 26, 2025

Generative modeling of molecular dynamics trajectories

Python 156 23 Updated Apr 5, 2025
Jupyter Notebook 202 20 Updated Sep 9, 2024

[AAAI 2025] Dynamic Protein Data Bank

Python 761 132 Updated May 28, 2025

Analysis of contacts in molecular dynamics trajectories

Python 42 13 Updated Nov 4, 2019

Contact map analysis for biomolecules based on MDTraj

Python 1 Updated Aug 9, 2023

The Binding Affinity Tool (BAT.py) is a fully automated tool for absolute binding free energy (ABFE) and relative binding free energy (RBFE) calculations on protein-ligand systems, compatible with …

Python 202 48 Updated Jun 12, 2025
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