unease

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From Middle English unese, equivalent to un- +‎ ease. Compare disease.

unease (uncountable)

1. Trouble; misery; a feeling of disquiet or concern.

• disease, dis-ease
• uneasiness

• uneasy

From Middle English unesen, equivalent to un- +‎ ease.

unease (third-person singular simple present uneases, present participle uneasing, simple past and past participle uneased)

1. (transitive) To make uneasy or uncomfortable.
   • 1981, Donna Weiss, Jackie DeShannon (lyrics and music), “Bette Davis Eyes”, performed by Kim Carnes:

     And she'll tease you / She'll unease you / All the better just to please you

• uneased

• usneae