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Oxazolidone can refer to any of three classes of five-membered ring heterocyclic compounds. The parents have the formula (CH2)2ONHCO, consisting of a carbonyl center, two methylene groups, an NH, and an O. These five entities give rise to C3NO rings. The isomer]]s are labeled 2-oxazolidones, 3-oxazolidones, and 4-oxazolidones.[1] 2-Oxazolidones, cyclic urethanes are the most common. 3- and 4-Oxazolidones, which have N-O bonds, are less common.

Cycloserine is an example of a 3-oxazolidinone.[2]

References

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  1. ^ Fernandes, Guilherme Felipe Santos; Scarim, Cauê Benito; Kim, Seong-Heun; Wu, Jingyue; Castagnolo, Daniele (2023). "Oxazolidinones as versatile scaffolds in medicinal chemistry". RSC Medicinal Chemistry. 14 (5): 823–847. doi:10.1039/D2MD00415A.
  2. ^ Polc P, Pieri L, Bonetti EP, Scherschlicht R, Moehler H, Kettler R, Burkard W, Haefely W (April 1986). "L-cycloserine: behavioural and biochemical effects after single and repeated administration to mice, rats and cats". Neuropharmacology. 25 (4). Elsevier BV: 411–418. doi:10.1016/0028-3908(86)90236-4. PMID 3012401. S2CID 462885.