Ornithine oxoglutarate

Ornithine oxoglutarate
	Ornithine (top) and ketoglutaric acid (bottom)
Clinical data
ATC code	A05BA06 (WHO) ;
Identifiers
	IUPAC name 2-Oxopentanedioic acid - L-ornithine (1:1);
CAS Number	34414-83-0 ;
PubChem CID	78866;
ChemSpider	71201;
CompTox Dashboard (EPA)	DTXSID30958449 DTXSID20187988, DTXSID30958449 ;
ECHA InfoCard	100.047.261 100.023.615, 100.047.261
Chemical and physical data
Formula	C10H18N2O7
Molar mass	278.261 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C(C[C@@H](C(=O)O)N)CN.C(CC(=O)O)C(=O)C(=O)O;
	InChI InChI=1S/C5H12N2O2.C5H6O5/c6-3-1-2-4(7)5(8)9;6-3(5(9)10)1-2-4(7)8/h4H,1-3,6-7H2,(H,8,9);1-2H2,(H,7,8)(H,9,10)/t4-;/m0./s1; Key:SLPUVFBNQHVEEU-WCCKRBBISA-N;
	(verify)

Ornithine oxoglutarate (OGO) or ornithine α-ketoglutarate (OKG) is a drug used in liver therapy. It is the salt formed from ornithine and alpha-ketoglutaric acid. It is also used to improve nutritional health in elderly patients.^[1]^[2]

References

^ Blonde-Cynober F, Aussel C, Cynober L (January 2003). "Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients". Nutrition. 19 (1): 73–5. doi:10.1016/S0899-9007(02)00849-3. PMID 12507647.
^ Brocker P, Vellas B, Albarede JL, Poynard T (July 1994). "A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects". Age and Ageing. 23 (4): 303–6. doi:10.1093/ageing/23.4.303. PMID 7976777.

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[1] Blonde-Cynober F, Aussel C, Cynober L (January 2003). "Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients". Nutrition. 19 (1): 73–5. doi:10.1016/S0899-9007(02)00849-3. PMID 12507647.

[2] Brocker P, Vellas B, Albarede JL, Poynard T (July 1994). "A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects". Age and Ageing. 23 (4): 303–6. doi:10.1093/ageing/23.4.303. PMID 7976777.

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[2]

v t e Bile and liver therapy (A05)
Bile therapy	bile acid Chenodeoxycholic acid Cholic acid Obeticholic acid Ursodeoxycholic acid Ursodoxicoltaurine Cyclobutyrol Elafibranor Hymecromone Maralixibat chloride Menbutone Nicotinyl methylamide Odevixibat Piprozolin Seladelpar
Liver therapy	Arginine glutamate Citiolone Epomediol Glycyrrhizin Metadoxine Methionine Ornithine oxoglutarate Phospholipids Silymarin Tidiacic arginine