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Level Set Framework of Multi Labels Fusion for Multiple Sclerosis Lesion Segmentation

Published: 13 October 2018 Publication History

Abstract

Multiple sclerosis (MS) lesion segmentation is important in estimating the progress of the disease and measuring the impact of new clinical treatments. In this paper, we present a multi-label fusion embedded level set method for White Matter (WM) lesion segmentation from Multiple Sclerosis (MS) patient images. Specifically we focus on the validation of the variational level set method. Lesion segmentation is achieved by extending the level set contour which consists of a label fusion term, an image data term and a regularization term. Labels are obtained from the fuzzy C-means model and embedded into the label fusion term. To compare the performance of our method with other state-of-the-art methods, we evaluated the methods with 20 MRI datasets of MS patients. Our approach exhibits a significantly higher accuracy on segmention of WM lesions over other evaluated methods.

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  1. Level Set Framework of Multi Labels Fusion for Multiple Sclerosis Lesion Segmentation

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    ISICDM 2018: Proceedings of the 2nd International Symposium on Image Computing and Digital Medicine
    October 2018
    166 pages
    ISBN:9781450365338
    DOI:10.1145/3285996
    Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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    • University of Electronic Science and Technology of China: University of Electronic Science and Technology of China

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    Published: 13 October 2018

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    Author Tags

    1. MRI
    2. Multiple sclerosis lesion
    3. fuzzy C-means
    4. level set
    5. multi-atlas

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