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A precision autozero amplifier for EEG signals

Published: 06 September 2010 Publication History

Abstract

Amplifiers for biological signals aimed to implantable medical devices require high gain and low noise, while maintaining very low power consumption. Therefore, a major challenge is the design of efficient low-noise circuits. These amplifiers work at low frequency ranging from sub-Hz to few kHz, thus besides the presence of thermal (white) noise, flicker noise (1/f noise) can be the largest. Autozero technique is used to reduce offset and flicker noise. However, a main issue in this kind of amplifiers is the aliasing of white noise inherit to the switching process, which increases the noise floor at low frequencies. In this work, the design of a low-noise amplifier for electroencephalography (EEG) signal recording is presented. The Autozero technique is applied to an instrumentation amplifier in the range of biological signals, with the addition of a low-pass filter in the noise cancellation feedback with the objective of reducing the impact of aliasing. Time domain simulations of the proposed amplifier show the benefits of the used architecture.

References

[1]
Matías Miguez, "Gm-C chopper amplifiers for implantable medical devices", MSc.Thesis, Universidad Católica del Uruguay, March 2008, http://die.ucu.edu.uy/microdie/publ.html.
[2]
A.Arnaud, C.Galup-Montoro, "Consistent Noise Models for Analysis and Design of CMOS Circuits", IEEE TCAS I, Vol.51, pp.1909--1915, Oct. 2004.
[3]
Denison, T.; Consoer, K.; Kelly, A.; Hachenburg, A.; Santa, W.; "A 2.2W 94nV/Hz, Chopper-Stabilized Instrumentation Amplifier for EEG Detection in Chronic Implants," Solid-State Circuits Conference, 2007. ISSCC 2007. Digest of Technical Papers. IEEE International, vol., no., pp.162--594, 11--15 Feb. 2007.
[4]
C. C. Enz and G. C. Temes, "Circuit techniques for reducing the effects of op-amp imperfections: Autozeroing, correlated double sampling, and chopper stabilization," Proc. IEEE, vol. 84, no. 11, pp. 1584--1614, Nov. 1996.
[5]
Yamu Hu, "CMOS Low Voltage Preamplifier Based On 1/f Noise Cancellation", MsC. Thesis, Université de Montréal, Dec. 2000.
[6]
Jader A. De Lima, "A Compact Low-Distortion Low-Power Instrumentation Amplifier", Proceedings of the 22nd Annual Symposium on Integrated Circuits and System Design - SBCCI 09, Natal, Brazil, Sept.2009.
[7]
A. Arnaud, M. Bremermann, J.Gak, M.Miguez, "On the design of ultra low noise amplifiers for ENG recording", 20th Symposium on Integrated Circuits and Systems Design - SBCCI 09, Rio de Janeiro, Brazil, Sept.2007.
[8]
http://www.mentor.com/

Cited By

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  • (2024)A high-speed autozeroing comparator with reduced current consumption2024 Panhellenic Conference on Electronics & Telecommunications (PACET)10.1109/PACET60398.2024.10497026(1-4)Online publication date: 28-Mar-2024
  • (2015)Modeling of neural networks based on transient response analysis of EEG signals from Broca's area2015 International Conference on Signal Processing and Communication Engineering Systems10.1109/SPACES.2015.7058218(72-76)Online publication date: Jan-2015
  • (2012)Biosensor Technologies for Augmented Brain–Computer Interfaces in the Next DecadesProceedings of the IEEE10.1109/JPROC.2012.2184829100:Special Centennial Issue(1553-1566)Online publication date: May-2012

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Published In

cover image ACM Conferences
SBCCI '10: Proceedings of the 23rd symposium on Integrated circuits and system design
September 2010
228 pages
ISBN:9781450301527
DOI:10.1145/1854153
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Publication History

Published: 06 September 2010

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Author Tags

  1. CMOS
  2. analog design
  3. autozero
  4. low-noise
  5. low-power

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Overall Acceptance Rate 133 of 347 submissions, 38%

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Cited By

View all
  • (2024)A high-speed autozeroing comparator with reduced current consumption2024 Panhellenic Conference on Electronics & Telecommunications (PACET)10.1109/PACET60398.2024.10497026(1-4)Online publication date: 28-Mar-2024
  • (2015)Modeling of neural networks based on transient response analysis of EEG signals from Broca's area2015 International Conference on Signal Processing and Communication Engineering Systems10.1109/SPACES.2015.7058218(72-76)Online publication date: Jan-2015
  • (2012)Biosensor Technologies for Augmented Brain–Computer Interfaces in the Next DecadesProceedings of the IEEE10.1109/JPROC.2012.2184829100:Special Centennial Issue(1553-1566)Online publication date: May-2012

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