[go: up one dir, main page]
More Web Proxy on the site http://driver.im/ skip to main content
research-article

Singularity Formation in Chemotaxis--- A Conjecture of Nagai

Published: 01 January 2004 Publication History

Abstract

Consider the initial-boundary value problem for the system (S)ut = uxx - (uvx)x, vt= u- av on an interval [0,1] for t > 0, where a > 0 with ux(0,t) = ux(1,t)= 0. Suppose \mu, v0 are positive constants. The corresponding spatially homogeneous global solution U(t) = \mu, V(t) = \mu a + (v0 - \mu a)\exp(-at) is stable in the sense that if (\mu',v0' ) are positive constants, the corresponding spatially homogeneous solution will be uniformly close to (U(\cdot),V(\cdot)).
We consider, in sequence space, an approximate system (S') which is related to (S) in the following sense: The chemotactic term (uvx)x is replaced by the inverse Fourier transform of the finite part of the convolution integral for the Fourier transform of (uvx)x. (Here the finite part of the convolution on the line at a point x of two functions, f,g, is defined as $\int_0^x(f(y)g(y-x)\,dy$.) We prove the following: If \mu > a, then in every neighborhood of (\mu,v0 ) there are (spatially nonconstant) initial data for which the solution of problem (S') blows up in finite time in the sense that the solution must leave L2 (0,1)\times H1 (0,1) in finite time T. Moreover, the solution components u(\cdot,t),v(\cdot,t) each leave L2 (0,1).If \mu > a, then in every neighborhood of (\mu,v0 ) there are (spatially nonconstant) initial data for which the solution of problem (S) on (0,1) \times (0,Tmax ) must blow up in finite time in the sense that the coefficients of the cosine series for (u,v) become unbounded in the sequence product space $\ell^1\times\ell^1_1$.
A consequence of (2) states that in every neighborhood of (\mu,v0 ), there are solutions of (S) which, if they are sufficiently regular, will blow up in finite time. (Nagai and Nakaki [Nonlinear Anal., 58 (2004), pp. 657--681] showed that for the original system such solutions are unstable in the sense that if \mu > a, then in every neighborhood of (\mu,\mu a), there are spatially nonconstant solutions which blow up in finite or infinite time. They conjectured that the blow-up time must be finite.) Using a recent regularity result of Nagai and Nakaki, we prove this conjecture.

References

[1]
Piotr Biler, Local and global solutions of a nonlinear nonlocal parabolic problem, GAKUTO Internat. Ser. Math. Sci. Appl., Vol. 7, Gakkōtosho, Tokyo, 1996, 49–66
[2]
Piotr Biler, Global solutions to some parabolic‐elliptic systems of chemotaxis, Adv. Math. Sci. Appl., 9 (1999), 347–359
[3]
S. Childress, J. Percus, Nonlinear aspects of chemotaxis, Math. Biosci., 56 (1981), 217–237
[4]
Burgess Davis, Reinforced random walk, Probab. Theory Related Fields, 84 (1990), 203–229
[5]
Jesus Diaz, Toshitaka Nagai, Jean‐Michel Rakotoson, Symmetrization techniques on unbounded domains: application to a chemotaxis system on RN, J. Differential Equations, 145 (1998), 156–183
[6]
Elizabeth Allman, John Rhodes, Mathematical models in biology: an introduction, Cambridge University Press, 2004xiv+370
[7]
Marco Fontelos, Avner Friedman, Bei Hu, Mathematical analysis of a model for the initiation of angiogenesis, SIAM J. Math. Anal., 33 (2002), 1330–1355
[8]
M. Herrero, E. Medina, J. Velázquez, Self‐similar blow‐up for a reaction‐diffusion system, J. Comput. Appl. Math., 97 (1998), 99–119
[9]
Miguel Herrero, Juan Velázquez, Chemotactic collapse for the Keller‐Segel model, J. Math. Biol., 35 (1996), 177–194
[10]
Miguel Herrero, Juan Velázquez, Singularity patterns in a chemotaxis model, Math. Ann., 306 (1996), 583–623
[11]
T. Hillen, H. Levine, Blow‐up and pattern formation in hyperbolic models for chemotaxis in 1‐D, Z. Angew. Math. Phys., 54 (2003), 839–868, Special issue dedicated to Lawrence E. Payne
[12]
T. Hillen and A. Potapov, The one‐dimensional chemotaxis model: Global existence and asymptotic profile, MMAS, to appear.
[13]
W. Jäger, S. Luckhaus, On explosions of solutions to a system of partial differential equations modelling chemotaxis, Trans. Amer. Math. Soc., 329 (1992), 819–824
[14]
E. Keller, Assessing the Keller‐Segel model: how has it fared?, Lecture Notes in Biomath., Vol. 38, Springer, Berlin, 1980, 379–387
[15]
E. F. Keller and L. A. Segel, Initiation of slime mold aggregation viewed as an instability, J. Theoret. Biol., 26 (1970), pp. 399–415.
[16]
E. F. Keller and L. A. Segel, Model for chemotaxis, J. Theoret. Biol., 30 (1971), pp. 225–234.
[17]
Howard Levine, Brian Sleeman, A system of reaction diffusion equations arising in the theory of reinforced random walks, SIAM J. Appl. Math., 57 (1997), 683–730
[18]
Toshitaka Nagai, Tatsuyuki Nakaki, Stability of constant steady states and existence of unbounded solutions in time to a reaction‐diffusion equation modelling chemotaxis, Nonlinear Anal., 58 (2004), 657–681
[19]
Toshitaka Nagai, Takasi Senba, Global existence and blow‐up of radial solutions to a parabolic‐elliptic system of chemotaxis, Adv. Math. Sci. Appl., 8 (1998), 145–156
[20]
Koichi Osaki, Atsushi Yagi, Finite dimensional attractor for one‐dimensional Keller‐Segel equations, Funkcial. Ekvac., 44 (2001), 441–469
[21]
Hans Othmer, Angela Stevens, Aggregation, blowup, and collapse: the ABCs of taxis in reinforced random walks, SIAM J. Appl. Math., 57 (1997), 1044–1081
[22]
Clifford Patlak, Random walk with persistence and external bias, Bull. Math. Biophys., 15 (1953), 311–338
[23]
Yin Yang, Hua Chen, Weian Liu, On existence of global solutions and blow‐up to a system of the reaction‐diffusion equations modelling chemotaxis, SIAM J. Math. Anal., 33 (2001), 763–785

Cited By

View all

Recommendations

Comments

Please enable JavaScript to view thecomments powered by Disqus.

Information & Contributors

Information

Published In

cover image SIAM Journal on Applied Mathematics
SIAM Journal on Applied Mathematics  Volume 65, Issue 1
2004
360 pages
ISSN:0036-1399
DOI:10.1137/smjmap.2004.65.issue-1
Issue’s Table of Contents

Publisher

Society for Industrial and Applied Mathematics

United States

Publication History

Published: 01 January 2004

Author Tags

  1. 35K55
  2. 92C17

Author Tags

  1. chemotaxis
  2. finite time singularity formation
  3. Keller--Segel model

Qualifiers

  • Research-article

Contributors

Other Metrics

Bibliometrics & Citations

Bibliometrics

Article Metrics

  • Downloads (Last 12 months)0
  • Downloads (Last 6 weeks)0
Reflects downloads up to 26 Jan 2025

Other Metrics

Citations

Cited By

View all

View Options

View options

Figures

Tables

Media

Share

Share

Share this Publication link

Share on social media