[go: up one dir, main page]
More Web Proxy on the site http://driver.im/ skip to main content
10.1007/978-3-030-68763-2_32guideproceedingsArticle/Chapter ViewAbstractPublication PagesConference Proceedingsacm-pubtype
Article

Deep Learning Based Segmentation of Breast Lesions in DCE-MRI

Published: 10 January 2021 Publication History

Abstract

Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) is a popular tool for the diagnosis of breast lesions due to its effectiveness, especially in a high risk population. Accurate lesion segmentation is an important step for subsequent analysis, especially for computer aided diagnosis systems. However, manual breast lesion segmentation of (4D) MRI is time consuming, requires experience, and it is prone to interobserver and intraobserver variability. This work proposes a deep learning (DL) framework for segmenting breast lesions in DCE-MRI using a 3D patch based U-Net architecture. We perform different experiments to analyse the effects of class imbalance, different patch sizes, optimizers and loss functions in a cross-validation fashion using 46 images from a subset of a challenging and publicly available dataset not reported to date, that is the TCGA-BRCA. We also compare the proposed U-Net framework with another state-of-the-art approach used for breast lesion segmentation in DCE-MRI, and report better segmentation accuracy with the proposed framework. The results presented in this work have the potential to become a publicly available benchmark for this task.

References

[1]
Badrinarayanan V, Kendall A, and Cipolla R SegNet: a deep convolutional encoder-decoder architecture for image segmentation IEEE Trans. Pattern Anal. Mach. Intell. 2017 39 12 2481-2495
[2]
Bria A, Karssemeijer N, and Tortorella F Learning from unbalanced data: a cascade-based approach for detecting clustered microcalcifications Med. Image Anal. 2014 18 2 241-252
[3]
Chen M, Zheng H, Lu C, Tu E, Yang J, and Kasabov N Cheng L, Leung ACS, and Ozawa S A spatio-temporal fully convolutional network for breast lesion segmentation in DCE-MRI Neural Information Processing 2018 Cham Springer 358-368
[4]
Clark K et al. The Cancer Imaging Archive (TCIA): maintaining and operating a public information repository J. Digit. Imaging 2013 26 6 1045-1057
[5]
Degani H, Gusis V, Weinstein D, Fields S, and Strano S Mapping pathophysiological features of breast tumors by MRI at high spatial resolution Nat. Med. 1997 3 7 780-782
[6]
DeSantis CE et al. Breast cancer statistics, 2019 CA Cancer J. Clin. 2019 69 6 438-451
[7]
El Adoui M, Mahmoudi S, Larhmam A, and Benjelloun M MRI breast tumor segmentation using different encoder and decoder CNN architectures J. Comput. 2019 8 52
[8]
Gubern-Mérida A et al. Automated localization of breast cancer in DCE-MRI Med. Image Anal. 2014 20 1 265-274
[9]
Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), pp. 3431–3440 (2015)
[10]
Piantadosi, G., Marrone, S., Galli, A., Sansone, M., Sansone, C.: DCE-MRI breast lesions segmentation with a 3TP U-Net deep convolutional neural network. In: 2019 IEEE 32nd International Symposium on Computer-Based Medical Systems (CBMS), pp. 628–633. IEEE (2019)
[11]
Ronneberger O, Fischer P, and Brox T Navab N, Hornegger J, Wells WM, and Frangi AF U-Net: convolutional networks for biomedical image segmentation Medical Image Computing and Computer-Assisted Intervention — MICCAI 2015 2015 Cham Springer 234-241
[12]
Subbhuraam VS, Ng E, Acharya UR, and Faust O Breast imaging: a survey World J. Clin. Oncol. 2011 2 4 171-178
[13]
Vignati A et al. Performance of a fully automatic lesion detection system for breast DCE-MRI J. Magn. Reson. Imaging JMRI 2011 34 6 1341-1351
[14]
Zhang J, Gao Y, Park SH, Zong X, Lin W, and Shen D Structured learning for 3-D perivascular space segmentation using vascular features IEEE Trans. Biomed. Eng. 2017 64 12 2803-2812
[15]
Zhang J, Saha A, Zhu Z, and Mazurowski MA Hierarchical convolutional neural networks for segmentation of breast tumors in MRI with application to radiogenomics IEEE Trans. Med. Imaging 2019 38 435-447
[16]
Zhang L, Luo Z, Chai R, Arefan D, Sumkin J, and Wu S Chen PH and Bak PR Deep-learning method for tumor segmentation in breast DCE-MRI Medical Imaging 2019: Imaging Informatics for Healthcare, Research, and Applications 2019 SPIE International Society for Optics and Photonics 97-102
[17]
Zheng Y, Baloch S, Englander S, Schnall MD, and Shen D Ayache N, Ourselin S, and Maeder A Segmentation and classification of breast tumor using dynamic contrast-enhanced MR images Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007 2007 Heidelberg Springer 393-401
[18]
Çiçek Ö, Abdulkadir A, Lienkamp SS, Brox T, and Ronneberger O Ourselin S, Joskowicz L, Sabuncu MR, Unal G, and Wells W 3D U-Net: learning dense volumetric segmentation from sparse annotation Medical Image Computing and Computer-Assisted Intervention – MICCAI 2016 2016 Cham Springer 424-432

Cited By

View all
  • (2023)Diffusion Kinetic Model for Breast Cancer Segmentation in Incomplete DCE-MRIMedical Image Computing and Computer Assisted Intervention – MICCAI 202310.1007/978-3-031-43901-8_10(100-109)Online publication date: 8-Oct-2023
  • (2022)A U-Net Ensemble for breast lesion segmentation in DCE MRIComputers in Biology and Medicine10.1016/j.compbiomed.2021.105093140:COnline publication date: 6-May-2022

Recommendations

Comments

Please enable JavaScript to view thecomments powered by Disqus.

Information & Contributors

Information

Published In

cover image Guide Proceedings
Pattern Recognition. ICPR International Workshops and Challenges: Virtual Event, January 10–15, 2021, Proceedings, Part I
Jan 2021
756 pages
ISBN:978-3-030-68762-5
DOI:10.1007/978-3-030-68763-2
  • Editors:
  • Alberto Del Bimbo,
  • Rita Cucchiara,
  • Stan Sclaroff,
  • Giovanni Maria Farinella,
  • Tao Mei,
  • Marco Bertini,
  • Hugo Jair Escalante,
  • Roberto Vezzani

Publisher

Springer-Verlag

Berlin, Heidelberg

Publication History

Published: 10 January 2021

Author Tags

  1. Breast Cancer
  2. DCE-MRI
  3. Breast lesions segmentation
  4. 3D U-Net

Qualifiers

  • Article

Contributors

Other Metrics

Bibliometrics & Citations

Bibliometrics

Article Metrics

  • Downloads (Last 12 months)0
  • Downloads (Last 6 weeks)0
Reflects downloads up to 03 Jan 2025

Other Metrics

Citations

Cited By

View all
  • (2023)Diffusion Kinetic Model for Breast Cancer Segmentation in Incomplete DCE-MRIMedical Image Computing and Computer Assisted Intervention – MICCAI 202310.1007/978-3-031-43901-8_10(100-109)Online publication date: 8-Oct-2023
  • (2022)A U-Net Ensemble for breast lesion segmentation in DCE MRIComputers in Biology and Medicine10.1016/j.compbiomed.2021.105093140:COnline publication date: 6-May-2022

View Options

View options

Media

Figures

Other

Tables

Share

Share

Share this Publication link

Share on social media