3D reconstruction of both shape and bone mineral density distribution of the femur from DXA images
Authors: 
Ludovic Humbert, Tristan Whitmarsh, Mathieu De Craene, Luis Miguel del Río Barquero, Karl Fritscher, Rainer Schubert, Felix Eckstein, Thomas Link, Alejandro F. FrangiAuthors Info & Claims
Pages 456 - 459
Abstract
The diagnosis of osteoporosis and the prevention of femur fractures is a major challenge for our society. However, the diagnosis performed in clinical routine from Dual Energy X-ray Absorptiometry (DXA) images is limited. This paper proposes a 3D reconstruction method of both the shape and the Bone Mineral Density (BMD) distribution of the proximal femur from routinely used DXA images. The reconstruction accuracy that can be obtained from single-view and multi-view DXA devices was assessed. This evaluation, from 20 bone specimens and simulated DXA images, highlighted a mean shape accuracy of 1.3mm and a BMD accuracy of 4.4% from a single-view DXA image. A multi-view configuration with 2 views (frontal-sagittal) appeared as a good compromise (mean shape accuracy of 0.9mm and BMD accuracy of 3.2%). We are currently using this method for in vivo clinical studies in order to improve the diagnosis of osteoporosis and the prevention of femur fractures.
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Published In
April 2010
1438 pages
ISBN:9781424441259
Publisher
IEEE Press
Publication History
Published: 14 April 2010
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