Comprehensive benchmarking of SNV callers for highly admixed tumor data
Fig 1
Schematic overview of “gold standard” variants in the simulated data set.
Moving from outer to inner circle, the circles show chromosomes, genomic regions covered in the exome experiments (dark blue), genomic regions in the panel regions (light blue), density of germline and somatic SNVs combined (dark green; maximum of scale at 3,000), density of somatic SNVs (green; maximum at 30), density of germline SNVs (light green; maximum at 3,000), density of germline and somatic indels (dark orange; maximum at 300), density of somatic indels (orange; maximum at 30), and density of germline indels (light orange; maximum at 300). Variant densities were computed in 1 Mb bins.