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Soluble CD163 as a Marker of Macrophage Activity in Newly Diagnosed Patients with Multiple Sclerosis

Figure 3

ROC curves generated for serum sCD163, CSF sCD163, sCD163 CSF/serum ratio, sCD163 Index, and IgG Index.

AUC, with 95% CI, is given for each parameter. The parameter results for patients with MS/CIS are combined as true positives and plotted against SC as true negatives. The diagonal dividing the ROC space represents the random event. Abbreviations: ROC (receiver operating characteristic), AUC (area under the curve), CIS (clinically isolated syndrome), SC (symptomatic controls), CSF (cerebrospinal fluid), CI (confidence interval).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0098588.g003