Macrophage Depletion Impairs Corneal Wound Healing after Autologous Transplantation in Mice
Figure 2
Sub-conjunctival Cl2MDP-LIP injection prevented the infiltration of macrophages.
Corneal flat mount staining after 14 days of penetrating keratoplasty showed a number of F4/80+ macrophages near the suture sites and around the junction between the graft and recipient cornea (A, B). Section staining primarily revealed staining clustered in the superficial corneal stromal layer (C), while few macrophages could be found in the junction and suture area in Cl2MDP-LIP-injected mice (D–F).