Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity
Figure 4
Succinate dehydrogenase activity was measured in (A) SIRT3 WT and KO MEF extracts (n = 4), (B) liver mitochondria (n = 3) and (C) brown adipose tissue (BAT) mitochondria (n = 6–7). SDH activity was normalized to sample protein content and expressed as a ratio of WT levels. Values are expressed as mean ±SEM. *, P<0.05.