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A multi-agent system for automated genomic annotation

Published: 28 May 2001 Publication History

Abstract

Massive amounts of raw data are currently being generated by biologists while sequencing organisms. Outside of the largest, high-profile projects such as the Human Genome Project, most of this raw data must be analyzed through the piecemeal application of various computer programs and searches of various public web databases. Due to the inexperience and lack of training, both the raw data and any valuable derived knowledge will remain generally unavailable except in published textual forms.
Multi-agent information gathering systems have a lot to contribute to these efforts, even at the current state of the art. We have used DECAF, a multi-agent system toolkit based on RETSINA and TAEMS, to construct a prototype multi-agent system for automated annotation and database storage of sequencing data for herpesviruses. The resulting system eliminates tedious and always out-of-date hand analyses, makes the data and annotations available for other researchers (or agent systems), and provides a level of query processing beyond even some high-profile web sites.

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cover image ACM Conferences
AGENTS '01: Proceedings of the fifth international conference on Autonomous agents
May 2001
662 pages
ISBN:158113326X
DOI:10.1145/375735
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Published: 28 May 2001

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  1. information agents
  2. lessons learned from deployed agents

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AGENTS01: Autonomous Agents 2001
Quebec, Montreal, Canada

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AGENTS '01 Paper Acceptance Rate 66 of 248 submissions, 27%;
Overall Acceptance Rate 182 of 599 submissions, 30%

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  • (2008)An agent framework integrated with Web Services for Grid computing2008 IEEE International Conference on Automation and Logistics10.1109/ICAL.2008.4636293(982-986)Online publication date: Sep-2008
  • (2008)Using BioAgents for Supporting Manual Annotation on Genome Sequencing ProjectsProceedings of the 3rd Brazilian symposium on Bioinformatics: Advances in Bioinformatics and Computational Biology10.1007/978-3-540-85557-6_12(127-139)Online publication date: 28-Aug-2008
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  • (2002)A Multi-agent Bioinformatics Integration System with Adjustable AutonomyPRICAI 2002: Trends in Artificial Intelligence10.1007/3-540-45683-X_53(492-501)Online publication date: 21-Aug-2002
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