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Identification of stimulus-response relations for cultured neuronal networks using features of multiple temporal resolution levels

Published: 31 May 2022 Publication History

Abstract

In recent years cultured neuronal networks have been used with the aim of unraveling how biological information transmits between neurons. Investigating the evoked activities of cultured neuronal networks helps acquire a better understanding of neural decoding. However, it is still challenging to quantitatively describe and predict evoked patterns for them. This study focuses on evoked patterns of cultured neuronal networks and aims to identify stimulus-response relations with extracted feature sets including spike-based and rate-based features. The majority of neural information is encoded in evoked activities of the post-stimulus intervals. By partitioning post-stimulus intervals, features with multiple temporal resolution levels were constructed. This study investigates the impact of temporal resolution level on accuracy in recognizing stimulus-response relations.

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BIC '22: Proceedings of the 2022 2nd International Conference on Bioinformatics and Intelligent Computing
January 2022
551 pages
ISBN:9781450395755
DOI:10.1145/3523286
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Association for Computing Machinery

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Published: 31 May 2022

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Author Tags

  1. in-vivo neuronal networks
  2. stimulus-response relations
  3. temporal resolution

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