[go: up one dir, main page]
More Web Proxy on the site http://driver.im/ skip to main content
10.1145/3354031.3354046acmotherconferencesArticle/Chapter ViewAbstractPublication PagesicbipConference Proceedingsconference-collections
research-article

Computer Aided Annotation of Early Esophageal Cancer in Gastroscopic Images based on Deeplabv3+ Network

Published: 13 August 2019 Publication History

Abstract

The diagnoses of Early Esophageal Cancer (EEC) based on gastroscopic images is a challenging task in clinic, which relies heavily on subjective artificial detection and annotation. As a result, computer aided diagnosis (CAD) methods that support the clinicians become highly attractive. In this paper, we proposed a CAD method which realized the automatic detection and annotation of EEC lesions in gastroscopic images. The proposed method initially utilized an advanced Deep Learning (DL) network Deeplabv3+ to obtain a preliminary prediction of EEC regions. Then, a post-processing step which referenced the clinical requirements was designed and applied to get the final annotation results. Totally 3190 gastroscopic images of 732 patients were used in this work. The final experimental results show that the EEC detection rate of our method was 97.07%, and the mean Dice Similarity Coefficient (DSC) was 74.01%, which are higher than those of other state-of-the-are DL-based methods. In addition, the false positive output of our method is fewer. Therefore, the proposed method offers a good potential to aid the clinical diagnoses of EEC.

References

[1]
GLOBOCAN. Estimated cancer incidence, mortality and prevalence worldwide in 2012. International Agency for Research on Cancer-World Health Organization. 2012. Available at: http://globocan.iarc.fr/Pages/online.aspx. Accessed May 13, 2019.
[2]
Whiteman, D. C. 2014. Esophageal cancer: priorities for prevention. Curr. Epidemiol. Rep.1, 3 (Jul. 2014), 138--148. DOI= http://dx.doi.org/10.1007/s40471-014-0015-3.
[3]
Liedlgruber, M. and Uhl, A. 2011. Computer-aided decision support systems for endoscopy in the gastrointestinal tract: A review. IEEE Rev. Biomed. Eng. 2011. 4, 4 (Nov. 2011), 73--88. DOI= http://dx.doi.org/10.1109/RBME.2011.2175445.
[4]
Iakovidis, D. K. and Koulaouzidis, A. 2015. Software for enhanced video capsule endoscopy: challenges for essential progress. Nat. Rev. Gastro. Hepat. 12, 3 (Mar. 2015), 172--186. DOI= http://dx.doi.org/10.1038/nrgastro.2015.13.
[5]
Chen, Y. and Lee, J. 2012. A review of machine-vision-based analysis of wireless capsule endoscopy video. Diagn. Ther. Endosc. 2012 (Oct. 2012), 1--9. DOI= 10.1155/2012/418037.
[6]
Mori, Y., Kudo, S., Mohmed, H. E. N. and Misawa, M. 2018. Artificial intelligence and upper gastrointestinal endoscopy: current status and future perspective. Digest. Endosc. (Dec. 2018), DOI= http://dx.doi.org/10.1111/den.13317.
[7]
Zhu, Y., Wang, Q. C., Xu M. D., Zhang Z., Chen, J. and Zhong, Y. S. 2019. Application of convolutional neural network in the diagnosis of the invasion depth of gastric cancer based on conventional endoscopy. Gastrointestinal Endoscopy. Gastrointest. Endosc. 89, 4 (Apr. 2019), 806--817. DOI= http://dx.doi.org/10.1016/j.gie.2018.11.011.
[8]
Zhang, J., Saha, A., Zhu, Z. and Mazurowski, M. A. 2019. Hierarchical Convolutional Neural Networks for Segmentation of Breast Tumors in MRI with Application to Radiogenomics. IEEE T. Med. Imaging. 38, 2 (Feb. 2019), 435--447. DOI= http://dx.doi.org/10.1109/tmi.2018.2865671.
[9]
Van Riel, S., Van Der Sommen, F., Zinger, S. and Schoon, E. 2018. Automatic Detection of Early Esophageal Cancer with CNNS Using Transfer Learning. In 25th IEEE International Conference on Image Processing (Athens, Greece, Oct 7-10, 2018). 1383--1387. DOI= http://dx.doi.org/10.1109/icip.2018.8451771.
[10]
Van der Sommen, F., Klomp, S. R., Swager, A. F. and Zinger, S. 2018. Predictive features for early cancer detection in Barrett's esophagus using volumetric laser Endomicroscopy. Comput. Med. Imag. Grap. 67 (Jul. 2018), 9--20. DOI= http://dx.doi.org/10.1016/j.compmedimag.2018.02.007.
[11]
Van Der Sommen, F. and Schoon, E. J. 2014. Supportive automatic annotation of early esophageal cancer using local gabor and color features. Neurocomputing. 144, 1 (Nov. 2014), 92--106. DOI= http://dx.doi.org/10.1016/j.neucom.2014.02.066.
[12]
Horie, Y., Yoshio, T., Aoyama, K. and Yoshimizu, S. 2018. Diagnostic outcomes of esophageal cancer by artificial intelligence using convolutional neural networks. Gastrointest. Endosc. 89, 1 (Jan. 2019), 25--32. DOI= http://dx.doi.org/10.1016/j.gie.2018.07.037.
[13]
Vasilakakis, M., Koulaouzidis, A., Yung, D. E., Plevris, J. N., Toth, E. and Iakovidis, D. K. 2018. Follow-up on: optimizing lesion detection in small bowel capsule endoscopy and beyond: from present problems to future solutions. Expert Rev. Gastroent. 13, 2 (Feb. 2019), 129--141. DOI= 10.1080/17474124.2019.1553616.
[14]
Iakovidis, D. K., Georgakopoulos, S. V., Vasilakakis, M., Koulaouzidis, A. and Plagianakos, V. P. 2018. Detecting and Locating Gastrointestinal Anomalies Using Deep Learning and Iterative Cluster Unification. IEEE T. Med. Imaging. 37, 10 (Oct. 2018), 2196--2210. DOI= http://dx.doi.org/10.1109/tmi.2018.2837002.
[15]
Liu, D. Y., Gan, T., Rao, N. N. and Xing, Y. W. 2016. Identification of lesion images from gastrointestinal endoscope based on feature extraction of combinational methods with and without learning process. Med. Image Anal. 32 (Aug. 2016), 281--294. DOI= http://dx.doi.org/10.1016/j.media.2016.04.007.
[16]
Chen, L. C., Zhu, Y., Papandreou, G. and Schroff, F. 2018. Encoder-decoder with atrous separable convolution for semantic image segmentation. In Proceedings of the European Conference on Computer Vision (Munich, Germany, Sep. 8-14, 2018). 801--818. DOI= http://dx.doi.org/10.1007/978-3-030-01234-2_49.
[17]
Chen, L.C., Papandreou, G., Schroff, F. and Adam, H. 2017. Rethinking atrous convolution for semantic image segmentation. arXiv:1706.05587 (Dec. 2017).
[18]
Dice, L. R. 1945. Measures of the Amount of Ecologic Association Between Species. Ecology. 26, 3 (Jul. 1945), 297--302. DOI= http://dx.doi.org/10.2307/1932409.
[19]
Liu, D. Y., Rao, N. N., Mei, X. M. and Jiang, H. X. 2018. Annotating Early Esophageal Cancers Based on Two Saliency Levels of Gastroscopic Images. J. Med. Syst. 42, 12 (Dec. 2018), 237. DOI= http://dx.doi.org/10.1007/s10916-018-1063-x.
[20]
Ronneberger, O., Fischer, P. and Brox, T. 2015. U-net: convolutional networks for biomedical image segmentation. In: Proceedings of the Medical Image Computing and Computer-Assisted Intervention. 9351 (2015) 234--241. DOI= http://dx.doi.org/10.1007/978-3-319-24574-4_28.
[21]
Badrinarayanan, V., Kendall A. and Cipolla, R. 2017. SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation. IEEE. T. Pattern. Anal. 39, 12 (Dec. 2017), 2481--2495. DOI= http://dx.doi.org/10.1109/TPAMI.2016.2644615.
[22]
Wang, P., Xiao, X., Glissen Brown, J. R. and Berzin, T. M. 2018. Development and validation of a deep-learning algorithm for the detection of polyps during colonoscopy. Nat. Biomed. Eng. 2, 10 (Oct. 2018), 741--748. DOI= http://dx.doi.org/10.1038/s41551-018-0301-3.
[23]
Litjens, G., Kooi, T., Bejnord, B. E. and Setio, A. A. A. 2017. A survey on deep learning in medical image analysis. Med. Image Anal. 42 (Dec. 2017), 60--88. DOI= http://dx.doi.org/10.1016/j.media.2017.07.005.
[24]
Nida, N., Irtaza, A., Javed, A. and Yousaf, M. H. 2019. Melanoma lesion detection and segmentation using deep region based convolutional neural network and fuzzy C-means clustering. Int. J. Med. Inform. 124 (Apr. 2019), 37--48. DOI= http://dx.doi.org/10.1016/j.ijmedinf.2019.01.005.

Cited By

View all
  • (2023)A Lightweight High-Resolution RS Image Road Extraction Method Combining Multi-Scale and Attention MechanismIEEE Access10.1109/ACCESS.2023.331339011(108956-108966)Online publication date: 2023
  • (2023)Classification of Esophageal Cancer Using Ensembled CNN with Generalized Normal Distribution Optimization Model and Support Vector Machine ClassifierCongress on Smart Computing Technologies10.1007/978-981-99-2468-4_8(83-111)Online publication date: 11-Jul-2023
  • (2022)Nasopharyngeal Organ Segmentation Algorithm Based on Dilated Convolution Feature PyramidThe International Conference on Image, Vision and Intelligent Systems (ICIVIS 2021)10.1007/978-981-16-6963-7_4(45-58)Online publication date: 3-Mar-2022
  • Show More Cited By

Index Terms

  1. Computer Aided Annotation of Early Esophageal Cancer in Gastroscopic Images based on Deeplabv3+ Network

      Recommendations

      Comments

      Please enable JavaScript to view thecomments powered by Disqus.

      Information & Contributors

      Information

      Published In

      cover image ACM Other conferences
      ICBIP '19: Proceedings of the 4th International Conference on Biomedical Signal and Image Processing
      August 2019
      149 pages
      ISBN:9781450372244
      DOI:10.1145/3354031
      Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

      In-Cooperation

      • Graduate School of Library, Information, and Media Studies, University of Tsukuba, Japan: Graduate School of Library, Information, and Media Studies, University of Tsukuba, Japan
      • Sichuan University

      Publisher

      Association for Computing Machinery

      New York, NY, United States

      Publication History

      Published: 13 August 2019

      Permissions

      Request permissions for this article.

      Check for updates

      Author Tags

      1. Deep learning
      2. Early esophageal cancer
      3. Gastroscopic image
      4. Lesion annotation

      Qualifiers

      • Research-article
      • Research
      • Refereed limited

      Funding Sources

      Conference

      ICBIP '19

      Contributors

      Other Metrics

      Bibliometrics & Citations

      Bibliometrics

      Article Metrics

      • Downloads (Last 12 months)8
      • Downloads (Last 6 weeks)3
      Reflects downloads up to 11 Dec 2024

      Other Metrics

      Citations

      Cited By

      View all
      • (2023)A Lightweight High-Resolution RS Image Road Extraction Method Combining Multi-Scale and Attention MechanismIEEE Access10.1109/ACCESS.2023.331339011(108956-108966)Online publication date: 2023
      • (2023)Classification of Esophageal Cancer Using Ensembled CNN with Generalized Normal Distribution Optimization Model and Support Vector Machine ClassifierCongress on Smart Computing Technologies10.1007/978-981-99-2468-4_8(83-111)Online publication date: 11-Jul-2023
      • (2022)Nasopharyngeal Organ Segmentation Algorithm Based on Dilated Convolution Feature PyramidThe International Conference on Image, Vision and Intelligent Systems (ICIVIS 2021)10.1007/978-981-16-6963-7_4(45-58)Online publication date: 3-Mar-2022
      • (2020)Multiple Linear Discriminant Models for Extracting Salient Characteristic Patterns in Capsule Endoscopy Images for Multi-Disease DetectionIEEE Journal of Translational Engineering in Health and Medicine10.1109/JTEHM.2020.29646668(1-11)Online publication date: 2020
      • (2020)Artificial Intelligence and Its Role in Identifying Esophageal NeoplasiaDigestive Diseases and Sciences10.1007/s10620-020-06643-265:12(3448-3455)Online publication date: 15-Oct-2020

      View Options

      Login options

      View options

      PDF

      View or Download as a PDF file.

      PDF

      eReader

      View online with eReader.

      eReader

      Media

      Figures

      Other

      Tables

      Share

      Share

      Share this Publication link

      Share on social media