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Wheezing Sound Separation Based on Constrained Non-Negative Matrix Factorization

Published: 16 May 2018 Publication History

Abstract

Auscultation remains the first clinical examination that a physician performs to detect respiratory diseases originated by wheezes, which are the most specific asthmatic symptoms. It is common that respiratory sounds (normal breath sounds) acoustically interfere wheezes with both frequency and time domain. As a result, the physician's cognitive ability is reduced causing a misdiagnosis or inability to clearly hear all significant sounds to detect a pulmonary disease. This paper presents a constrained non-negative matrix factorization (NMF) approach to separate wheezes from respiratory sounds applied to single-channel mixtures. The proposed constraints, smoothness and sparseness, attempts to model common spectral behaviour shown by wheezes and normal breath sounds. Specifically, the spectrogram of a wheeze can be modelled as a narrowband spectrum (sparseness in frequency). However, the spectrogram of a normal breath sound can be modelled as a wideband spectrum (smoothness in frequency) with a slow temporal variation (smoothness in time). Experimental results report that the proposed method improves the audio quality of the wheezes removing most of the respiratory sounds, being a novel way to successfully apply a NMF approach to a wheeze/respiratory sound separation.

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Cited By

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  • (2022)An ambient denoising method based on multi-channel non-negative matrix factorization for wheezing detectionThe Journal of Supercomputing10.1007/s11227-022-04706-x79:2(1571-1591)Online publication date: 29-Jul-2022
  • (2021)Monophonic and Polyphonic Wheezing Classification Based on Constrained Low-Rank Non-Negative Matrix FactorizationSensors10.3390/s2105166121:5(1661)Online publication date: 28-Feb-2021
  • (2020)Wheezing Sound Separation Based on Informed Inter-Segment Non-Negative Matrix Partial Co-FactorizationSensors10.3390/s2009267920:9(2679)Online publication date: 8-May-2020

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    ICBBT '18: Proceedings of the 2018 10th International Conference on Bioinformatics and Biomedical Technology
    May 2018
    93 pages
    ISBN:9781450363662
    DOI:10.1145/3232059
    Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than the author(s) must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected].

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    • Universidade Nova de Lisboa

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    New York, NY, United States

    Publication History

    Published: 16 May 2018

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    Author Tags

    1. Constraint
    2. Non-negative matrix factorization (NMF)
    3. Respiratory
    4. Smoothness
    5. Sparseness
    6. Wheeze

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    View all
    • (2022)An ambient denoising method based on multi-channel non-negative matrix factorization for wheezing detectionThe Journal of Supercomputing10.1007/s11227-022-04706-x79:2(1571-1591)Online publication date: 29-Jul-2022
    • (2021)Monophonic and Polyphonic Wheezing Classification Based on Constrained Low-Rank Non-Negative Matrix FactorizationSensors10.3390/s2105166121:5(1661)Online publication date: 28-Feb-2021
    • (2020)Wheezing Sound Separation Based on Informed Inter-Segment Non-Negative Matrix Partial Co-FactorizationSensors10.3390/s2009267920:9(2679)Online publication date: 8-May-2020

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