research-article

The Dermal Abyss: Color-Changing Tattoos for Medical Diagnostics

Authors:

Xin Liu,

Joe ParadisoAuthors Info & Claims

GetMobile: Mobile Computing and Communications, Volume 22, Issue 2

Pages 38 - 42

https://doi.org/10.1145/3276145.3276158

Published: 05 September 2018 Publication History

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Abstract

Can tattoos reveal changes in human physiology? The Dermal Abyss (d-abyss) presents an approach to biointerfaces in which the body surface is rendered an interactive display. Traditional tattoo inks are replaced with biosensors whose colours or intensity change in response to variations of biomarkers in the interstitial fluid. The Dermal Abyss is designed to use the aesthetics, permanence, and visible nature of tattoos to encode diagnostic information. Here, tattoo biosensors were designed to report on the concentration of sodium ions, glucose, and pH in the skin. We report the preliminary quantitative evaluation of these biosensors in an ex vivo skin model by assessing their visibility of color changes from the dermis. This work provides a proof of concept of a platform in which the skin reveals information inside the body, tattoos form wearable displays within the skin, and the body's metabolism works as an input for the d-abyss biosensors.

References

[1]

Bandodkar, A. J., Hung, V. W., Jia, W., Valdes- Ram?rez, G., Windmiller, J. R., Martinez, A. G., Ram?rez, J., Chan, G., Kerman, K., and Wang, J. "Tattoo-based potentiometric ion-selective sensors for epidermal ph monitoring." Analyst, 138, 1 (2013), 123-128.

Crossref

Google Scholar

[2]

Bandodkar, A. J., Jia, W., Yard?mc?, C., Wang, X., Ramirez, J., and Wang, J. "Tattoo-based noninvasive glucose monitoring: a proof-ofconcept study." Analytical Chemistry, 87, 1 (2014), 394-398.

Google Scholar

[3]

Deter-Wolf, A., Robitaille, B., Krutak, L., and Galliot, S. "The world's oldest tattoos." Journal of Archaeological Science, Reports 5 (2016), 19-24.

Crossref

Google Scholar

[4]

Diastix. Urine test strips, 2015. https://www. healthwarehouse.com/diastix-urine-reagentstrips- 50-urinalysis-strips.html

Google Scholar

[5]

Kim, D. H., Lu, N., Ma, R., Kim, Y. S., Kim, R. H., Wang, S., Yu, K. J. (2011). "Epidermal Electronics." Science, 333(6044), 838-843.

Google Scholar

[6]

Mostafalu, P., Akbari, M., Alberti, K. A., Xu, Q., Khademhosseini, A., and Sonkusale, S. R. "A toolkit of thread-based microfluidics, sensors, and electronics for 3d tissue embedding for medical diagnostics." Microsystems & Nanoengineering 2 (2016).

Google Scholar

[7]

Phan, C.-M., Subbaraman, L., and Jones, L. W. "The use of contact lenses as biosensors." Optometry & Vision Science 93, 4 (2016), 419-425.

Crossref

Google Scholar

[8]

Ring, C. M., and Cohen, P. J. "Cryosurgery for tattoo removal." In Dermatological Cryosurgery and Cryotherapy. Springer, 2016, 609-610.

Google Scholar

[9]

Scallan, J., Huxley, V.H. and Korthuis, R.J. "Capillary Fluid Exchange: Regulation, Functions, and Pathology" in Colloquium Lectures on Integrated Systems Physiology From Molecules to Function 2, (Morgan & Claypool Life Sciences, 2009-10), 1-94.

Google Scholar

[10]

Shibata, H., Heo, Y. J., Okitsu, T., Matsunaga, Y., Kawanishi, T., and Takeuchi, S. "Injectable hydrogel microbeads for fluorescence-based in vivo continuous glucose monitoring." Proceedings of the National Academy of Sciences 107, 42 (2010), 17894-17898.

Crossref

Google Scholar

[11]

Vega, K., and Fuks, H. "Beauty technology: Body surface computing." Computer 47, 4 (2014), 71-75.

Digital Library

Google Scholar

[12]

Vega, K., Jiang, N., Liu, X., Kan, V., Barry, N., Maes, P., Yetisen, A. and Paradiso, J., 2017, September. "The dermal abyss: Interfacing with the skin by tattooing biosensors." In Proceedings of the 2017 ACM International Symposium on Wearable Computers (pp. 138-145). ACM.

Digital Library

Google Scholar

[13]

Yetisen, A.K., Butt, H., Volpatti, L.R., Pavlichenko, I., Humar, M., Kwok, S.J., Koo, H., Kim, K.S., Naydenova, I., Khademhosseini, A. and Hahn, S.K. "Photonic hydrogel sensors." Biotechnology Advances 34, 3 (2016), 250-271.

Crossref

Google Scholar

[14]

Yetisen, A.K., Martinez-Hurtado, J.L., Ünal, B., Khademhosseini, A. and Butt, H., 2018. "Wearables in medicine." Advanced Materials, p.1706910.

Google Scholar

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Zhao YYan JCheng JFu YZhou JYan JGuo J(2024)Development of Flexible Electronic Biosensors for Healthcare EngineeringIEEE Sensors Journal10.1109/JSEN.2023.328729124:8(11998-12016)Online publication date: 15-Apr-2024
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BOUTET-DIÉYE ASEZNEC A(2022)Les représentations des tatouages connectés: enjeux de l’acceptabilité et relation à l’imaginaireTic & société10.4000/ticetsociete.6427Vol. 15, N° 2-3(101-125)Online publication date: 2022
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Published In

cover image GetMobile: Mobile Computing and Communications

GetMobile: Mobile Computing and Communications Volume 22, Issue 2

June 2018

38 pages

ISSN:2375-0529

EISSN:2375-0537

DOI:10.1145/3276145

Editor:
Eyal de Lara
University of Toronto

Issue’s Table of Contents

Publisher

Association for Computing Machinery

New York, NY, United States

Publication History

Published: 05 September 2018

Published in SIGMOBILE-GETMOBILE Volume 22, Issue 2

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Cited By

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Zhao YYan JCheng JFu YZhou JYan JGuo J(2024)Development of Flexible Electronic Biosensors for Healthcare EngineeringIEEE Sensors Journal10.1109/JSEN.2023.328729124:8(11998-12016)Online publication date: 15-Apr-2024
https://doi.org/10.1109/JSEN.2023.3287291
Rasheed SKanwal TAhmad NFatima BNajam-ul-Haq MHussain D(2024)Advances and challenges in portable optical biosensors for onsite detection and point-of-care diagnosticsTrAC Trends in Analytical Chemistry10.1016/j.trac.2024.117640(117640)Online publication date: Mar-2024
https://doi.org/10.1016/j.trac.2024.117640
BOUTET-DIÉYE ASEZNEC A(2022)Les représentations des tatouages connectés: enjeux de l’acceptabilité et relation à l’imaginaireTic & société10.4000/ticetsociete.6427Vol. 15, N° 2-3(101-125)Online publication date: 2022
https://doi.org/10.4000/ticetsociete.6427
Gardner JKao HNetravali A(2022)Biodegradable Bio-based Material for Wearable Air Filtering SkinAdjunct Proceedings of the 2022 ACM International Joint Conference on Pervasive and Ubiquitous Computing and the 2022 ACM International Symposium on Wearable Computers10.1145/3544793.3560320(35-37)Online publication date: 11-Sep-2022
https://dl.acm.org/doi/10.1145/3544793.3560320
Pourjafarian NKoelle MFruchard BMavali SKlamka KGroeger DStrohmeier PSteimle JKitamura YQuigley AIsbister KIgarashi TBjørn PDrucker S(2021)BodyStylus: Freehand On-Body Design and Fabrication of Epidermal InterfacesProceedings of the 2021 CHI Conference on Human Factors in Computing Systems10.1145/3411764.3445475(1-15)Online publication date: 6-May-2021
https://dl.acm.org/doi/10.1145/3411764.3445475

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