Integrative Database for Exploring Compound Combinations of Natural Products for Medical Effects
Authors: 
Suhyun Ha, Sunyong Yoo, Moonshik Shin, Jin Sook Kwak, Oran Kwon, Min Chang Choi, Keon Wook Kang, Hojung Nam, Doheon LeeAuthors Info & Claims
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Abstract
Natural products used in dietary supplements, complementary and alternative medicine (CAM) and conventional medicine are composites of multiple chemical compounds. These chemical compounds potentially offer an extensive source for drug discovery with accumulated knowledge of efficacy and safety. However, existing natural product related databases have drawbacks in both standardization and structuralization of information. Therefore, in this work, we construct an integrated database of natural products by mapping the prescription, herb, compound, and phenotype information to international identifiers and structuralizing the efficacy information through database integration and text-mining methods. We expect that the constructed database could serve as a fundamental resource for the natural products research.
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R Xue et al. TCMID: traditional Chinese medicine integrative database for herb molecular mechanism analysis. Nucleic Acids Research (2013)
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X Chen et al. Database of traditional Chinese medicine and its application to studies of mechanism and to prescription validation. British Journal of Pharmacology (2006)
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Korean Traditional Knowledge Portal (KTKP): http://www.koreantk.com
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Japanese Traditional Medicine and Therapeutics (KAMPO): http://www.kampo.ca
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Aronson AR. Effective mapping of biomedical text to the UMLS Metathesaurus: the MetaMap program. Proceedings of the AMIA Symposium (2001)
Index Terms
- Integrative Database for Exploring Compound Combinations of Natural Products for Medical Effects
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Published In
November 2014
60 pages
ISBN:9781450312752
DOI:10.1145/2665970
- General Chairs:
- Doheon Lee,
- Luonan Chen,
- Program Chairs:
- Hua Xu,
- Min Song
Copyright © 2014 Owner/Author.
Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for third-party components of this work must be honored. For all other uses, contact the Owner/Author.
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Association for Computing Machinery
New York, NY, United States
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Published: 07 November 2014
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CIKM '14: 2014 ACM Conference on Information and Knowledge Management
November 7, 2014
Shanghai, China
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DTMBIO '14 Paper Acceptance Rate 22 of 211 submissions, 10%;
Overall Acceptance Rate 41 of 247 submissions, 17%
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