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Multilayered Particles Based on Biopolyelectrolytes as Potential Peptide Delivery Systems

  • ON THE 80th ANNIVERSARY OF THE BIRTH OF A.B. ZEZIN
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Abstract

A series of amphiphilic charged copolymers of amino acids is synthesized, and their binding to cationic and anionic peptides is studied. The resulting interpolyelectrolyte complexes are additionally stabilized by cationic/anionic polysaccharides using surface layering. The positive effect of coatings on the release rate of peptides and decrease in the cytotoxicity and increase in the stability of the resulting peptide delivery systems in biological media is shown.

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REFERENCES

  1. Z. Niu, I. Conejos-Sánchez, B. T. Griffin, C. M. O’Driscoll, and M. J. Alonso, Adv. Drug Delivery Rev. 106, 337 (2016).

    Article  CAS  Google Scholar 

  2. R. Gupta and S. Mohanty, Colloids Surf., B 154, 48 (2017).

    Article  CAS  Google Scholar 

  3. B. Bumbaca, Z. Li, and D. K. Shah, Drug Metab. Pharmacokinet. 34, 42 (2019).

    Article  CAS  Google Scholar 

  4. O. K. Faber, C. Hagen, and C. Binder, J. Clin. Invest. 62, 197 (1978).

    Article  CAS  Google Scholar 

  5. A. Wanger, V. Chavez, R. S. P. Huang, A. Wahed, J. K. Actor, and A. Dasgupta, Microbiology and Molecular Diagnosis in Pathology. A Comprehensive Review for Board Preparation, Certification and Clinical Practice (Elsevier, Amsterdam, 2017).

    Google Scholar 

  6. X. Zhang, H. Wang, Z. Ma, and B. Wu, Expert Opin. Drug Metab. Toxicol. 10, 1691 (2014).

    Article  CAS  Google Scholar 

  7. C. G. Jolivalt, M. Rodriguez, J. Wahren, and N. A. Calcutt, Diabetes, Obes. Metab. 3, 147 (2016).

    Google Scholar 

  8. C. L. Nemeth, W. R. Lykins, H. Tran, M. E. H. Elsayed, and T. A. Desai, Pharm. Res. 36, 89 (2019).

    Article  Google Scholar 

  9. M. R. Kim, T. Feng, Q. Zhang, H. Y. E. Chan, and Y. Chau, Polymers 11, 288 (2019).

    Article  Google Scholar 

  10. G. Hetényi, J. Griesser, M. Moser, F. Demarne, V. Jannin, and A. Bernkop-Schnürch, Int. J. Pharm. 523, 357 (2017).

    Article  Google Scholar 

  11. G. R. Agrawal, P. Wakte, and S. Shelke, Prog. Biomater. 6, 125 (2017).

    Article  CAS  Google Scholar 

  12. K. Bloch, A. Vanichkin, I. Gil-Ad, P. Vardi, and A. Weizman, J. Tissue Eng. Regener. Med. 11, 3263 (2017).

    Article  CAS  Google Scholar 

  13. S. S. Saravanan, M. S. Malathi, S. S. Selvasubramanian, B. S. Balasubramanian, and P. V. Pandiyan, Int. J. Biol. Macromol. 95, 1190 (2017).

    Article  CAS  Google Scholar 

  14. V. B. V. Maciel, C. M. P. Yoshida, S. M. S. S. Pereira, F. M. Goycoolea, and T. T. Franco, Molecules 22, 1707 (2017).

    Article  Google Scholar 

  15. M. Alibolandi, F. Alabdollah, F. Sadeghi, M. Mohammadi, K. Abnous, M. Ramezani, and F. Hadizadeh, J. Controlled Release 227, 58 (2016).

    Article  CAS  Google Scholar 

  16. P. Severino, M. V. Chaud, A. Shimojo, D. Antonini, M. Lancelloti, M. H. A. Santana, and E. B. Souto, Colloids Surf., B 129, 191 (2015).

    Article  CAS  Google Scholar 

  17. S. R. Shah, A. M. Henslee, P. P. Spicer, S. Yokota, S. Petrichenko, S. Allahabadi, G. N. Bennett, M. E. Wong, F. K. Kasper, and A. G. Mikos, Pharm. Res. 31, 3379 (2014).

    Article  CAS  Google Scholar 

  18. C. Tang, E. Zhang, Y. Li, and L. Yang, Eur. J. Pharm. Sci. 102, 63 (2017).

    Article  CAS  Google Scholar 

  19. M. Wang, C. Zhou, J, Chen, Y, Xiao, and J. Du, Bioconjug. Chem. 26, 725 (2015).

    Article  CAS  Google Scholar 

  20. L. Zhao, N. Li, K. Wang, C. Shi, L. Zhang, and Y. Luan, Biomaterials 35, 1284 (2014).

    Article  CAS  Google Scholar 

  21. K. Kita-Tokarczyk, J. Grumelard, T. Haefele, and W. Meier, Polymer 46, 3540 (2005).

    Article  CAS  Google Scholar 

  22. S. Pearson, D. Vitucci, Y. Y. Khine, A. Dag, H. Lu, M. Save, L. Billon, and M. H. Stenzel, Eur. Polym. J. 69, 616 (2015).

    Article  CAS  Google Scholar 

  23. H. Gao, Y. Tan, Q. Guan, T. Cai, G. Liang, and Q. WuQ, RSC Adv. 5, 49376 (2015).

  24. R. Sigel, M. Łosik, and H. Schlaad, Langmuir 23, 7196 (2007).

    Article  CAS  Google Scholar 

  25. H. Gao, G. Li, Z. Hu, Z. Xiao, G. Liang, and Q. Wu, Polymer 55, 4593 (2014).

    Article  CAS  Google Scholar 

  26. K. Osada, R. J. Christie, K. Kataoka, J. R. Soc., Interface 6 (Suppl. 3), 325 (2009).

    Google Scholar 

  27. C. Chen, L. Chen, H. Chen, H. Li, and M. Yuan, Polym. Bull. 70, 1739 (2013).

    Article  CAS  Google Scholar 

  28. R. P. Johnson, J. V. John, and I. Kim, Eur. Polym. J. 49, 2925 (2013).

    Article  CAS  Google Scholar 

  29. Y.-C. Huang, Y.-S. Yang, T.-Y. Lai, and J.-S. Jan, Polymer 53, 913 (2012).

    Article  CAS  Google Scholar 

  30. E. P. Holowka, D. J. Pochan, and T. J. Deming, J. Am. Chem. Soc. 127, 12423 (2005).

    Article  CAS  Google Scholar 

  31. Z. Liu, F. Zhou, J. Wu, Y. Yao, Y. Guo, X. Liao, F. Gao, and Y. Qian, J. Electroanal. Chem. 823, 253 (2018).

    Article  CAS  Google Scholar 

  32. N. N. Zashikhina, M. V. Volokitina, V. A. Korzhikov-Vlakh, I. I. Tarasenko, A. Lavrentieva, T. Scheper, E. Rühl, R. V. Orlova, T. B. Tennikova, E. G. Korzhikova-Vlakh, Eur. J. Pharm. Sci. 109, 1 (2017).

    Article  CAS  Google Scholar 

  33. J. Tang, J. Yao, J. Shi, Q. Xiao, J. Zhou, and F. Chen, Pharmazie. 67, 756 (2012).

    CAS  PubMed  Google Scholar 

  34. E. Vlakh, A. Ananyan, N. Zashikhina, A. Hubina, A. Pogodaev, M. Volokitina, V. Sharoyko, and T. Tennikova, Polymers 8, 212 (2016).

    Article  Google Scholar 

  35. Z. Zhao, Y. Wang, J. Han, K. Wang, D. Yang, Y. Yang, Q. Du, Y. Song, and X. Yin, Int. J. Nanomed. 9, 5849 (2014).

    Article  Google Scholar 

  36. I. Tarasenko, N. Zashikhina, I. Guryanov, M. Volokitina, B. Biond, S. Fiorucci, F. Formaggi, T. Tennikova, and E. Korzhikova-Vlakh, RSC Adv. 8, 34603 (2018).

  37. R. Wilder and S. Mobashery, J. Org. Chem. 57, 2755 (1992).

    Article  CAS  Google Scholar 

  38. H. R. Marsden, L. Gabrielli, and A. Kros, Polym. Chem. 1, 1512 (2010).

    Article  CAS  Google Scholar 

  39. Q. Guo, T. Zhang, J. An, Z. Wu, Y. Zhao, X. Dai, X. Zhang, and C. Li, Biomacromolecules 16, 3345 (2015).

    Article  CAS  Google Scholar 

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Funding

This study was supported by the Russian Science Foundation (project no. 19-73-20157).

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, 199004, St. Petersburg, Russia

    N. N. Zashikhina, I. I. Tarasenko & E. G. Korzhikova-Vlakh

  2. St. Petersburg State University, Institute of Chemistry, 198504, Peterhof, St. Petersburg, Russia

    D. V. Yudin, O. M. Osipova & E. G. Korzhikova-Vlakh

Authors
  1. N. N. Zashikhina
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  2. D. V. Yudin
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  3. I. I. Tarasenko
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  4. O. M. Osipova
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  5. E. G. Korzhikova-Vlakh
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Correspondence to E. G. Korzhikova-Vlakh.

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Zashikhina, N.N., Yudin, D.V., Tarasenko, I.I. et al. Multilayered Particles Based on Biopolyelectrolytes as Potential Peptide Delivery Systems. Polym. Sci. Ser. A 62, 43–53 (2020). https://doi.org/10.1134/S0965545X20010125

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  • DOI: https://doi.org/10.1134/S0965545X20010125

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