Due to the significance of hydrogen peroxide (H2O2) in biological systems and its practical applications, the development of efficient electrochemical H2O2 sensors holds a special attraction for researchers. Various materials such as Prussian blue (PB), heme proteins, carbon nanotubes (CNTs) and transition metals have been applied to the construction of H2O2 sensors. In this article, the electrocatalytic H2O2 determinations are mainly focused on because they can provide a superior sensing performance over non-electrocatalytic ones. The synergetic effect between nanotechnology and electrochemical H2O2 determination is also highlighted in various aspects. In addition, some recent progress for in vivo H2O2 measurements is also presented. Finally, the future prospects for more efficient H2O2 sensing are discussed.
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