In this issue, a large and multiscale whole-body model of organ-specific regulation and metabolism for type 1 diabetes is developed, providing important details on glucose and insulin dynamics.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
£14.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
£79.00 per year
only £6.58 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Williams, R. et al. IDF Diabetes Atlas 9th edn (IDF, 2019).
Guebila, M. B. & Thiele, I. Nat. Comput. Sci. https://doi.org/10.1038/s43588-021-00074-3 (2021).
Thiele, I. et al. Nat. Biotechnol. 31, 419–425 (2013).
Brunk, E. et al. Nat. Biotechnol. 36, 272–281 (2018).
Schaller, S. et al. CPT Pharmacom. Syst. Pharmacol. 2, e65 (2013).
Subramanian, A. et al. Cell 171, 1437–1452 (2017).
Beck, R. W., Connor, C. G., Mullen, D. M., Wesley, D. M. & Bergenstal, R. M. Diabetes Care 40, 994–999 (2017).
Thiele, I. et al. Mol. Syst. Biol. 16, e8982 (2020).
Meyer, M. R., Clegg, D. J., Prossnitz, E. R. & Barton, M. Acta Physiol. 203, 259–269 (2011).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Zhao, J., Xu, H. & Yang, L. A dynamic metabolic map for diabetes. Nat Comput Sci 1, 309–310 (2021). https://doi.org/10.1038/s43588-021-00075-2
Published:
Issue Date:
DOI: https://doi.org/10.1038/s43588-021-00075-2